AI Article Synopsis

  • - Breast mucoepidermoid carcinoma (MEC) is a rare type of cancer, accounting for only 0.2-0.3% of all breast tumors, with just 41 cases documented in medical literature.
  • - A 42-year-old Chinese woman was diagnosed with breast MEC after presenting with a lump; microscopic analysis revealed various cell types and specific markers that helped identify the tumor characteristics.
  • - Following a mastectomy, the patient was classified with low-grade mucoepidermoid carcinoma, highlighting the importance of accurate diagnosis to guide effective patient management.

Article Abstract

Breast mucoepidermoid carcinoma (MEC) is clinically rare, with an estimated incidence of 0.2-0.3% of all primary breast tumors. To date, only 41 cases have been reported in the literature. Herein, we present a case of breast MEC diagnosed at our hospital. The clinicopathologic features were preliminarily discussed by reviewing the literature. A 42-year-old Chinese woman presented with a lump in her right breast that was detected approximately three months prior. A microscopic examination showed that the breast MEC was composed of different proportions of mucinous cells, intermediate cells, and epidermoid cells. Most mucinous cells were positive for cytokeratin 7, while the epidermoid and intermediate cells were positive for p63 and cytokeratin 5/6. All tumor cells were negative for other myoepithelial markers, such as calponin. Tumor cells did not express estrogen, progesterone, or the HER-2/neu protein. After the patient underwent mastectomy, she was diagnosed with a low-grade mucoepidermoid carcinoma based on the clinical, histologic, and immuno-phenotypic characteristics. Our findings provide further insight into the pathologic mechanism of MEC, as correct diagnosis is essential for patient management.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7791392PMC

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