A positive direct antiglobulin test (DAT) and hemolytic anemia are uncommon side effect of cisplatin (CDDP) therapy. A 9-year-old girl treated for extraosseus Ewing's sarcoma with a multiagent regimen, including 200 mg/m2 CDDP preceded by vincristine (VCR) and cyclophosphamide (CY), developed a positive DAT, followed by hemolytic anemia. When CDDP therapy was discontinued, the DAT became negative and no signs of anemia were observed during the maintenance treatment, which included VCR and actinomycin D.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF00262747 | DOI Listing |
Publication Analysis
Top Keywords
positive direct
8
direct antiglobulin
8
antiglobulin test
8
dat hemolytic
8
hemolytic anemia
8
cddp therapy
8
test pediatric
4
pediatric patient
4
patient high-dose
4
high-dose cisplatin
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!