To investigate the larvicidal activities of novel anthraquinones () against mosquito larvae. Novel anthraquinones () derivatives were synthesis via condensation method. The compounds were confirmed through FT-IR spectroscopy, H & C NMR spectrum, and mass spectral studies. The larvicidal activity of compound was highly active LD 20.92 µg/mL against compared standard with LD 25.49 µg/mL. Molecular docking studies were carried out for compound against Odorant-binding protein of . The compound (-9.8 Kcal/mol) was a potent larvicide with more binding energy than control (-9.7 Kcal/mol). Therefore, compound () may be more significant inhibitors of mosquito larvicidal.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783635 | PMC |
http://dx.doi.org/10.1016/j.sjbs.2020.09.028 | DOI Listing |
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