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Association between intravesical prostatic protrusion and clinical outcomes in prostatic artery embolization. | LitMetric

Association between intravesical prostatic protrusion and clinical outcomes in prostatic artery embolization.

Diagn Interv Imaging

Department of Vascular and Oncological Interventional Radiology, AP-HP, centre, Hôpital Européen Georges-Pompidou, 75015 Paris, France; Université de Paris, 75006 Paris, France; INSERM URM 970 équipe 2 Imagerie de l'Angiogenèse, 75015 Paris, France.

Published: March 2021

AI Article Synopsis

  • The study aimed to assess how intravesical prostatic protrusion (IPP) affects outcomes after prostatic artery embolization (PAE) in men with urinary issues from benign prostatic hyperplasia.
  • It included 160 men, analyzing their IPP severity (graded from 1 to 3) and assessing symptoms through standardized questionnaires before and after the procedure.
  • Results showed that while severe IPP (grade 3) led to a more significant improvement in symptoms compared to non-severe cases, the overall efficacy of PAE was not hindered by the degree of IPP.

Article Abstract

Purpose: To evaluate the influence of intravesical prostatic protrusion (IPP) on clinical outcomes after prostatic artery embolization (PAE) in patients with lower urinary tract symptoms due to benign prostatic hyperplasia.

Materials And Methods: All consecutive patients who underwent PAE for lower urinary tract symptoms between January 2017 and January 2019 were retrospectively included. IPP was evaluated on pre-treatment magnetic resonance imaging examination and symptoms were assessed at follow-up consultations using the international prostate symptom score (IPSS) and quality of life (QOL) questionnaire. IPPs were classified as grade 1 (<5mm), grade 2 (5-10mm), or grade 3 (>10mm).

Results: A total of 160 consecutive men (mean age 65±7.8 [SD] years; range: 45-89 years), underwent PAE. The mean IPSS was 21±7.3 (SD) (range: 5-35) and prostate volume 87±38 (SD) mL (range: 30-200mL). The IPP grade was 1 for 28 (28/160; 18%), 2 for 52 (52/160; 33%), and 3 for 80 (80/160; 50%) patients. There were no significant differences in IPSS at baseline between the three IPP grades. Patients with severe (grade 3) IPP had a significantly higher reduction in IPSS than those with non-severe IPP (grade 1 or 2), with estimated mean reductions of 12±2.5 (SD) (range: -4-28) and 8.3±1.9 (SD) (range: -8-21) (P=0.02), respectively. The mean reduction in the QOL score was 3.0 for grade 3 and 2.0 for grade 1 or 2 IPP (P=0.02).

Conclusions: The degree of IPP does not limit the efficacy of PAE in patients with lower urinary tract symptoms due to benign prostatic hyperplasia.

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Source
http://dx.doi.org/10.1016/j.diii.2020.12.003DOI Listing

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