Introduction: Cocooning, the vaccination of close contacts of a newborn, is a strategy to limit the risk of pertussis and influenza infection among vulnerable infants.
Methods: Pregnant women in Colorado and Georgia referred close contacts to an app that provided tailored educational videos about vaccines along with a small pharmacy-based financial incentive for vaccine receipt. The primary objective of this study was to determine the feasibility of implementing this app-based cocooning intervention.
Results: Two hundred seventy seven contacts were enrolled in this study. Of those who received the educational videos, 96% found them interesting, 100% found them clear to understand, 97% found them helpful, and 99% trusted them. Completion of the videos led to significant increases in influenza vaccine knowledge (p = 0.025), Tdap vaccine knowledge (p < 0.001), and intention to receive these vaccines (p = 0.046). Of the 136 participants who reported receiving influenza vaccine, 41 (30%) reported receiving it at a pharmacy, and of the 66 who reported receiving Tdap vaccine, 15 (23%) reported receiving it at a pharmacy. Of all participants, 80% reported being comfortable receiving vaccines at a pharmacy instead of a doctor's office. The provision of small pharmacy-based financial incentives combined with individually-tailored educational videos about vaccines led to 6.97 (95%CI: 2.25-21.64) times higher odds of self-reported receipt of influenza vaccine than providing small pharmacy-based financial incentives without these videos. No significant difference was found for Tdap vaccine.
Conclusions: Tailored vaccine education can positively impact vaccine knowledge and intentions among adults. An app-based referral program providing education and financial incentives for cocooning vaccination at pharmacies is feasible.
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http://dx.doi.org/10.1016/j.vaccine.2020.12.067 | DOI Listing |
Vet Clin North Am Exot Anim Pract
December 2024
Department of Clinical Sciences, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USA. Electronic address:
Exotic pet ownership has steadily increased over the last decade, and with increased numbers of these species in close contact with humans, the risk of gastrointestinal zoonoses has also increased. Non-typhoidal serovars of Salmonella enterica are one of the most prevalent and important zoonoses of exotic pets, and reptile and backyard poultry are common asymptomatic carriers of these bacteria. Outbreaks of reptile-associated salmonellosis have occurred yearly in the United States since 2019 but contact with backyard poultry has actually been associated with more Salmonella outbreaks in the United States than any other animal species to date.
View Article and Find Full Text PDFPrimates
December 2024
Université de Strasbourg, IPHC UMR7178, CNRS, Strasbourg, France.
Huddling behaviour is present in many animal species. This behaviour involves maintaining close physical contact with conspecifics to minimise heat loss and, in general, reduce energy expenditure. Additionally, this behaviour also facilitates complex social interactions within a population.
View Article and Find Full Text PDFTrop Med Infect Dis
December 2024
Department of Community Medicine, Osun State University, Osogbo 230101, Nigeria.
Providing tuberculosis preventive treatment (TPT) to close contacts of persons with TB is a core strategy recommended by WHO for the prevention and control of TB. Nigeria rolled out the 3-month Isoniazid-Rifampicin (3HR) shorter regimen TPT as a pilot for use among eligible adult and child contacts. This study assesses acceptance and completion rates of 3HR TPT among contacts and determines the perspectives of healthcare workers (HCWs) and contacts on acceptance and completion of 3HR TPT in Nigeria.
View Article and Find Full Text PDFNanomaterials (Basel)
December 2024
College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Chiral molecules are ubiquitous in nature and biological systems, where the unique optical and physical properties of chiral nanoparticles are closely linked to their shapes. Synthesizing chiral plasmonic nanomaterials with precise structures and tunable sizes is essential for exploring their applications. This study presents a method for growing three-dimensional chiral gold nanoflowers (Au NFs) derived from trisoctahedral (TOH) nanocrystals using D-cysteine and L-cysteine as chiral inducers.
View Article and Find Full Text PDFBiosensors (Basel)
November 2024
Nano Electrochemistry Laboratory, College of Engineering, University of Georgia, Athens, GA 30602, USA.
Hepatitis A virus (HAV), a major cause of acute liver infections, is transmitted through the fecal-oral route and close contact with infected individuals. Current HAV standardized methods rely on the detection of virus antigen or RNA, which do not differentiate between infectious and non-infectious HAV. The objective of this study was to develop a prototype cell-based electrochemical biosensor for detection of infectious HAV.
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