Surgical outcomes and prognostic factors of parasagittal meningioma: a single-center experience 165 consecutive cases.

Purpose: This study aimed to estimate the prognostic factors, long-term outcomes, and surgical strategies for parasagittal meningioma (PSM) and provide a better understanding of surgical experience.

Materials And Methods: Patients ( = 1438) who underwent surgery for meningioma between January 2012 and January 2013 were enrolled in a database. We then identified 165 patients with PSM based on this database.

Results: Of the 165 patients with identified PSMs, 103 were female and 62 were male, with a mean age of 49 years. Univariate analysis revealed that male sex ( = .002), non-World Health Organization (WHO) grade I meningioma ( < .001), treatment history ( = .006), surgical time more than 232 minutes ( = .006), and intraoperative bleeding > 300mL ( = .019) were associated with decreased progression-free survival (PFS). Multivariate analysis revealed that sex (hazards ratio [HR] = 3.836, 95% confidence interval [CI] = 1.364-10.794;  = .011], tumour grade (HR = 8.479, 95% CI = 3.234-22.230;  < .001), and surgical time (HR = 3.710, 95% CI = 1.057-13.023;  = .041) were independent factors for PFS. Patients with Simpson grade I-II ( = .015), no-treatment history ( = .006), tumour size < 3cm ( = .005), surgical time < 232 minutes ( = .019), intraoperative bleeding < 300mL ( < .001), or WHO grade I meningioma ( = .002) had better follow-up conditions.

Conclusion: Surgery was an effective treatment for PSM, and at the time of final follow-up, patients who received aggressive resection had a substantially higher Karnofsky performance scale score.