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Substitution of liposomal bupivacaine for lidocaine reduces incidence of injection-emergent adverse events after intraarticular therapies for knee osteoarthritis: a prospective cohort study.
Int J Surg
December 2024
Department of Orthopaedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Abstract: Local anesthetics as a part of intraarticular therapies (IATs) are widely used for treating knee osteoarthritis (KOA). Whether substitution of liposomal bupivacaine (LB) for lidocaine is safe and effective in reducing incidence of injection-emergent adverse events after IATs remains unclear.
Methods: We recruited outpatients who had a clinical diagnosis of KOA and decided to receive IATs from November 2023 to April 2024.
Efficacy of a single central injection of lignocaine at the scrotal neck on the behavioural response of lambs to castration.
Vet Anaesth Analg
September 2024
CSIRO, Agriculture and Food, Armidale, Australia. Electronic address:
Objective: To compare the behavioural responses of lambs to ring castration with or without local anaesthetic administration by single midline injection at the scrotal neck.
Study Design: Blinded, randomized block design pen study.
Animals: A group of 60 male Merino lambs; 6-8 weeks of age; average body weight of 18.
WALANT vs standard anaesthesia in the management of flexor tendon injuries: A systematic review and meta-analysis.
J Hand Microsurg
December 2024
Department of Plastic Surgery, Leeds General Infirmary, Leeds, United Kingdom.
Wide awake local anaesthesia no tourniquet (WALANT) surgery has gained increasing popularity in recent years for hand surgery fast-tracked by the COVID pandemic. It involves infiltration of lidocaine with adrenaline to the operative region ensuring a good visual field owing to the vasoconstrictive effects of epinephrine. It has numerous advantages over traditional anaesthetic (TA) for flexor tendon repairs including testing of tendon strength on table as well as immediate revision of the repair if needed.
View Article and Find Full Text PDFCommentary on "Efficacy of 0.25% Lidocaine Versus 0.5% Lidocaine in Dermatologic Surgery: A Double-Blind, Randomized Controlled Trial".
Dermatol Surg
January 2025
Both authors are affiliated with the Department of Dermatology, Mayo Clinic, Jacksonville, Florida.
Objectives: Hysterectomy or myomectomy is a common gynaecological procedure that results in moderate to severe acute postoperative pain, which can cause many adverse effects. This study aimed to compare the postoperative analgesic efficacy, opioid consumption, quality of postoperative recovery (QOR) and adverse reactions of intravenous coinjection of lidocaine and dexmedetomidine versus lidocaine or dexmedetomidine alone in gynaecological surgery.
Design: Systematic review and meta-analysis was performed.
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