GSDME: A Potential Ally in Cancer Detection and Treatment.

Trends Cancer

Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43/6, 2650 Edegem, Antwerp, Belgium; Center for Oncological Research (CORE), Integrated Personalized and Precision Oncology Network (IPPON), University of Antwerp and Antwerp University Hospital, Universiteitsplein 1, 2610 Wilrijk, Antwerp, Belgium. Electronic address:

Published: May 2021

Gasdermin E (GSDME) is an executioner of caspase-3 mediated regulated pyroptosis, and as such plays an important role in several cancers. Recent findings highlighted the potential of GSDME as a biomarker that can be implemented in cancer diagnosis, monitoring, and therapy.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.trecan.2020.12.002DOI Listing

Publication Analysis

Top Keywords

gsdme potential
4
potential ally
4
ally cancer
4
cancer detection
4
detection treatment
4
treatment gasdermin
4
gasdermin gsdme
4
gsdme executioner
4
executioner caspase-3
4
caspase-3 mediated
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!