With the increase in data processing and storage capacity, a large amount of data is available [...].
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| http://dx.doi.org/10.3390/e22121438 | DOI Listing |
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Transcriptomic Profiles in Nasal Epithelium and Asthma Endotypes in Youth.
JAMA
January 2025
Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: T helper 2 (T2) cells and T helper 17 (T17) cells are CD4+ T cell subtypes involved in asthma. Characterizing asthma endotypes based on these cell types in diverse groups is important for developing effective therapies for youths with asthma.
Objective: To identify asthma endotypes in school-aged youths aged 6 to 20 years by examining the distribution and characteristics of transcriptomic profiles in nasal epithelium.
Neuropsychiatric Outcomes in Children and Adolescents with Perinatally Acquired HIV: A Systematic Review and Meta Analysis.
J Acquir Immune Defic Syndr
January 2025
Department of Psychiatry, University of Oxford, Oxford OX3 7JX, UK.
Objective: The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment and psychiatric illness faced by children with perinatally acquired HIV.
Data Sources: Nine databases were searched on 30/05/2023: MEDLINE, Embase, and PsycINFO (all via Ovid SP); CINAHL and Child Development and Adolescent Studies (via EBSCO); the Web of Science Core Collection; Scopus; ProQuest Dissertations and Theses Global; and WHO Global Index Medicus. No limits were applied.
A modified adaptive Kalman filter algorithm for the distributed underwater multi-target passive tracking system.
JASA Express Lett
January 2025
College of Information and Communication Engineering, Harbin Engineering University, Harbin, 150006, China.
A modified adaptive Kalman filter (AKF) algorithm is proposed to make underwater multi-target tracking with uncertain measurement noise reliable. By utilizing the proposed AKF algorithm with three core points, including an adaptive fading factor, measurement noise covariance adjustment, and an adaptive weighting factor, the unknown measurement noise and state vector can be estimated with good accuracy and robustness. The practical trial data verify this algorithm, and it has proven superior to all traditional algorithms in this Letter based on the results that it reduces the estimated position RMSEs by at least 10.
View Article and Find Full Text PDFGeographic Distribution of US Ophthalmic Surgical Subspecialists.
JAMA Ophthalmol
January 2025
The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Importance: While urban counties maintain higher densities of ophthalmologists than rural counties, the geographic distribution of ophthalmic surgical subspecialists has not yet been elucidated. A potential workforce discrepancy may impact the burden of care faced by rural surgeons.
Objective: To assess the geographic distribution of the ophthalmic subspecialist surgeon workforce and evaluate factors associated with practicing in rural areas.
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