Current concepts on the immune system, the genesis of human T- and B-lymphocytes, and their functional properties are presented as well as current data on the pathogenesis and classification of hereditary defects of the human immune system. The main forms of immunity deficiency conditions are described. The methods for diagnosis and treatment of different forms of immunologic deficiency are substantiated. The relationship between immunity deficiency conditions and malignancies, allergic and autoimmune processes, and morphological changes in various organs and tissues is described.

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