The Democratic Republic of the Congo (DRC) has begun implementing HIV self-testing to boost the first "95" of the UNAIDS 95-95-95 targets by 2025. This study aims to assess the performance and usability of the Exacto Test HIV (Biosynex, Strasbourg, France) self-test in the lab and in the field. The Exacto Test HIV self-test demonstrated high virological performance (sensitivity, 99.6%; specificity, 100%) in the lab and in the field in the hand of untrained users (sensitivity, 100%; specificity, 98.9%). Taken together, the excellent performance and usability characteristics of the Exacto Test HIV (Biosynex) self-test make the kit a viable option for HIV self-testing in the DRC.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759209 | PMC |
| http://dx.doi.org/10.1093/ofid/ofaa554 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Real-Life Clinical Outcomes of Benralizumab Treatment in Patients with Uncontrolled Severe Asthma and Coexisting Chronic Rhinosinusitis with Nasal Polyposis.
J Clin Med
July 2024
Pulmonology Department, Doctor Peset University Hospital, 46017 Valencia, Spain.
Article Synopsis
- The study aimed to assess the effectiveness of benralizumab in patients with severe asthma and chronic rhinosinusitis with nasal polyposis (CRSwNP) who were not well-controlled on standard treatment.
- After 12 months of treatment, significant improvements were observed: exacerbations dropped by 82%, steroid use decreased by 84%, and emergency visits were reduced by 83%.
- Additionally, lung function and nasal symptoms improved markedly, with over half of the patients achieving a "complete response" or "super response" after treatment.
Rapid tests should be used with caution for HIV-1 primary infection screening.
Med Microbiol Immunol
June 2024
Service de Virologie, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Paris, F- 75013, France.
Rapid tests allow outpatient, low cost, reliable, screening for chronic HIV infection. However, data regarding their sensitivity on primary infection remain scarce. The objective of this study was to assess sensitivity of nine HIV rapid tests for primary HIV-1 infection screening.
View Article and Find Full Text PDFFactors determining the resection ability of snares in cold snare polypectomy: Construction of an ex vivo model for accurately evaluating resection ability.
Dig Endosc
May 2024
Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Objectives: Cold snare polypectomy (CSP)-dedicated snares (DSs) may have a higher resection ability than conventional snares. However, a model that can accurately and objectively evaluate and compare the resection ability of each snare has yet to be determined, and characteristics of snare parts that increase resection ability remain unknown. Therefore, we elucidated DSs' resection ability and all characteristics of the parts required for acquiring high resection ability.
View Article and Find Full Text PDFDiagnostic accuracy of a rapid nucleic acid test for group A streptococcal pharyngitis using saliva samples: protocol for a prospective multicenter study in primary care.
Diagn Progn Res
July 2023
Centre of Research in Epidemiology and Statistics (Inserm UMR 1153), Université Paris Cité, Paris, France.
Article Synopsis
- Group A streptococcus causes 20-40% of childhood sore throats (pharyngitis), often requiring antibiotics only in bacterial cases; most guidelines suggest confirming infection before treatment.
- This study evaluates the effectiveness of a new saliva test (Abbott ID NOW STREP A2) for detecting group A streptococcus compared to the traditional throat swab test in children with pharyngitis.
- The research aims to recruit 800 children and will assess various outcomes, including sensitivity, result time, and satisfaction among patients and parents, to see if saliva testing is a viable and convenient alternative to throat swabs.
Effect of endodontic sealers on push-out bond strength of CAD-CAM or prefabricated fiber glass posts.
Braz Oral Res
June 2023
Instituto de Pesquisas São Leopoldo Mandic, São Leopoldo Mandic School of Dentistry, Department of Restorative Dentistry, Campinas, SP, Brazil.
This study aimed to evaluate the effect of endodontic sealer (ES) on bond strength (BS) of prefabricated or milled-CAD-CAM (computer-aided design and computer-aided manufacturing) glass-fiber-posts (GFP). Canals of 90 single-rooted teeth were prepared for filling by the single-cone technique with gutta-percha and one of the following ES: AH Plus (epoxy resin), Endofill (zinc-oxide and eugenol), and Bio-C Sealer (calcium-silicate). After post-space preparation, tooth-specimens were equally divided in half according to type of GFP to be used.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!