Background: The world is going through a pandemic caused by newly emerged "Novel Coronavirus," which was originated from Wuhan, China in December 2019. This pandemic caused havoc in the world. So far, more than 200 countries have been affected by Novel Coronavirus. India is also not untouched by this outbreak. The corona virus transmits through droplets, contact, and fomites in human and become a chain transmission by human to human. SARS-CoV-2 spread worldwide by air transport, and it is also reaches to local and small societies or villages by domestic transport through the travelers.
Methods: In this study, data are accessed from Ministry of Health and Family Affaires, Ministry of Home affairs, Ministry of Transport, Government of India, World health organization, and www.worldometers.info. The accessed data are analyzed by origin 6.1 software.
Results: In India, till April 8, 2020, 5274 people were found infected with COVID-19, out of which 410 were recovered, and the remaining 149 died. The infection of SARS-CoV-2 reaches to several places by international and domestic through human travelers. To avoid local and community transmission in India, it was decided for complete lockdown of 21 days from March 25, 2020 in country to prevent mass gathering and promote social distancing. Further, the lockdown was extended to May 3, 2020. The decision of lockdown has been successful in getting control of COVID-19 in India so far.
Conclusions: The effective measure of lockdown to control COVID-19 was found to be very successful in India and it can be apply by other countries to control the COVID-19.
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http://dx.doi.org/10.4103/jfmpc.jfmpc_692_20 | DOI Listing |
Hum Vaccin Immunother
December 2025
Research and Development, Infectious Disease, Moderna, Inc., Cambridge, MA, USA.
Safety, immunogenicity, and effectiveness of an mRNA-1273 50-μg booster were evaluated in adolescents (12-17 years), with and without pre-booster SARS-CoV-2 infection. Participants who had received the 2-dose mRNA-1273 100-µg primary series in the TeenCOVE trial (NCT04649151) were offered the mRNA-1273 50-μg booster. Primary objectives included safety and inference of effectiveness by establishing noninferiority of neutralizing antibody (nAb) responses after the booster compared with the nAb post-primary series of mRNA-1273 among young adults in COVE (NCT04470427).
View Article and Find Full Text PDFSwiss Med Wkly
December 2024
Center for Primary Care and Public Health (Unisanté), Department of Epidemiology and Health Systems, University of Lausanne, Lausanne, Switzerland.
Aim: To assess the perceptions of adults with diabetes regarding their care and health during the COVID-19 pandemic in the canton of Vaud, Switzerland.
Methods: Cross-sectional data was analysed from the 2021 follow-up questionnaire of the CoDiab-VD survey, a cohort of adults living with diabetes in the canton of Vaud. Various aspects of diabetes care and issues relating to the COVID-19 pandemic were assessed.
J Ultrasound Med
January 2025
Department of Emergency Medicine, The University of Arizona College of Medicine, Tucson, Arizona, USA.
Objectives: The prognostic characteristics of lung point-of-care ultrasound (L-POCUS) to predict respiratory decompensation in patients with emerging infections remains unstudied. Our objective was to examine whether scored lung ultrasounds predict hypoxia among a nonhypoxic, ambulatory population of patients with COVID-19.
Methods: This was a diagnostic case-control study.
Front Endocrinol (Lausanne)
January 2025
Boston College, William F. Connell School of Nursing, Boston, MA, United States.
Background: The effect of antidiabetic agents on mortality outcomes is unclear for individuals with diabetes mellitus (DM) who are hospitalized for COVID-19.
Purpose: To examine the relationship between antidiabetic agent use and clinical outcomes in individuals with DM hospitalized for COVID-19.
Methods: A systematic review of the literature (2020-2024) was performed across five databases.
Front Immunol
January 2025
Institute of Clinical Biochemistry, Hannover Medical School, Hannover, Germany.
Introduction: Serum levels of interleukin-6 (IL-6) are increased in COVID-19 patients. IL-6 is an effective therapeutic target in inflammatory diseases and tocilizumab, a monoclonal antibody that blocks signaling via the IL-6 receptor (IL-6R), is used to treat patients with severe COVID-19. However, the IL-6R exists in membrane-bound and soluble forms (sIL-6R), and the sIL-6R in combination with soluble glycoprotein 130 (sgp130) forms an IL-6-neutralizing buffer system capable of neutralizing small amounts of IL-6.
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