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| http://dx.doi.org/10.1186/s13023-020-01566-7 | DOI Listing |
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European clinical practice guideline: managing and treating laryngopharyngeal reflux disease.
Eur Arch Otorhinolaryngol
December 2024
Research Committee of Young-Otolaryngologists of the International Federations of Oto-rhino- laryngological Societies (YO-IFOS), Paris, France.
Objective: To propose a European consensus for managing and treating laryngopharyngeal reflux disease (LPRD) to guide primary care and specialist physicians.
Methods: Twenty-three European experts (otolaryngologists, gastroenterologists, surgeons) participated in a modified Delphi process to revise 38 statements about the definition, clinical management, and treatment of LPRD. Three voting rounds were conducted on a 5-point scale and a consensus was defined a priori as agreement by 80% of the experts.
Preadmission systemic antibiotic treatment in necrotizing otitis externa (NOE).
Eur Arch Otorhinolaryngol
December 2024
Department of Otolaryngology, Head and Neck Surgery, Sheba Medical Center, Tel Hashomer, Israel.
Purpose: Necrotizing otitis externa (NOE) is a serious life-threatening infection, with Pseudomonas (PA) aeruginosa being the primary causative agent. Over the last two decades the use of systemic anti-PA antibiotics expanded substantially and are now prescribed regularly by physicians. Meanwhile, studies indicate shifting trends in the incidence of the offending pathogen in NOE.
View Article and Find Full Text PDFStructure and composition of early biofilms formed on dental implants are complex, diverse, subject-specific and dynamic.
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Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Hannover, Germany.
Biofilm-associated peri-implant infections pose a major problem in modern medicine. The understanding of biofilm development is hampered by biofilm complexity and the lack of robust clinical models. This study comprehensively characterized the dynamics of early biofilm formation in the transmucosal passage of implant abutments in 12 patients.
View Article and Find Full Text PDFCluster randomised controlled trial of double-dose azithromycin mass drug administration, facial cleanliness and fly control measures for trachoma control in Oromia, Ethiopia: the stronger SAFE trial protocol.
BMJ Open
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Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
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View Article and Find Full Text PDFApplying 1-hour postload plasma glucose diagnostic criteria reveals high Progressive Risks of potential MASLD.
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Department of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, No. 58 Zhongshan II Road, Yuexiu District, Guangzhou, China. Electronic address:
Background: Recently, a 1-h PG value of ≥ 8.6 mmol/L, a more sensitive predictor of diabetes mellitus-related long-term cardiovascular complications than routine glucose markers, has been recommended as an additional diagnostic criterion for diabetes in the International Diabetes Federation Position Statement. However, its value in MASLD remains uncertain.
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