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Effects of time-restricted feeding in weight loss, metabolic syndrome and cardiovascular risk in obese women. | LitMetric

AI Article Synopsis

  • The study highlights the growing issue of overweight and obesity, linking it to health risks like Type 2 diabetes and cardiovascular diseases, particularly in those with metabolic syndrome (MetS).
  • The research aimed to assess the impact of time-restricted feeding (TRF) on body composition and the related health risks in obese middle-aged women over a 3-month period.
  • Results showed that TRF effectively reduced weight, BMI, and body fat percentage without significantly altering MetS-related blood biomarkers, while also lowering long-term cardiovascular risk by 12%.

Article Abstract

Background: The increasing prevalence of overweight and obesity among the worldwide population has been associated with a range of adverse health consequences such as Type 2 diabetes and cardiovascular diseases. The metabolic syndrome (MetS) is a cluster of cardiometabolic abnormalities that occur more commonly in overweight individuals. Time-restricted feeding (TRF) is a dietary approach used for weight loss and overall health. TRF may be an option for those subjects who struggle with extreme restriction diets with foods that generally do not belong to an individual's habits.

Objective: The purpose of this study was to determine the effect of TRF on body composition and the association of weight loss with metabolic and cardiovascular risks in obese middle-aged women.

Methods: A non-randomized controlled clinical trial was performed over 3 months in obese women (TRF group, n = 20, BMI 32.53 ± 1.13 vs. Control n = 12, BMI 34.55 ± 1.20). The TRF protocol adopted was 16 h without any energy intake followed by 8 h of normal food intake.

Main Outcomes And Measures: Anthropometric measurements, body composition, blood biomarkers, cardiovascular risk in 30 years (CVDRisk30y), and quality of life were evaluated at baseline and after the 3 months.

Results: TRF was effective in reducing weight (~ 4 kg), BMI, % of body fat (%BF), waist circumference from baseline without changes in blood biomarkers associated with MetS. TRF promoted a reduction in CVDRisk30y (12%) wich was moderately correlated with %BF (r = 0.62, n = 64, p < 0.001) and %MM (r = - 0.74, n = 64, p < 0.001).

Conclusions: TRF protocol reduces body weight without changes in biomarkers related to MetS. In addition, the anthropometric evaluation that predicts %BF and %MM could be used as an approach to follow individuals engaged in the TRF regimen since they correlate with cardiovascular risk.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786967PMC
http://dx.doi.org/10.1186/s12967-020-02687-0DOI Listing

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