Congenital heart surgeons' training is complex and challenging. The learning curve is long and the increasing complexity of pathologies is demanding. In order to develop adequate surgical-skill competencies, "in vivo" and simulation-based practicing are paramount. Simulation can be performed either on a computer screen or animal hearts and prosthetic models. In this article, we illustrate a porcine Wet Lab simulation for the Nikaidoh operation to point out its potential advantage to learn complex congenital surgery procedures.
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http://dx.doi.org/10.1177/2150135120957644 | DOI Listing |
Sci Rep
January 2025
Advanced Glass and Glass Ceramic Research Laboratory, Department of Physics, University of Lucknow, Lucknow, 226007, India.
Recently, 3-D porous architecture of the composites play a key role in cell proliferation, bone regeneration, and anticancer activities. The osteoinductive and osteoconductive properties of β-TCP allow for the complete repair of numerous bone defects. Herein, β-TCP was synthesized by wet chemical precipitation route, and their 3-D porous composites with HBO and Cu nanoparticles were prepared by the solid-state reaction method with improved mechanical and biological performances.
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January 2025
Environmental and Occupational Hazards Control Research Center, Research Institute for Health Sciences and Environment, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
The magnetic material Nd2Fe14B is one of the strongest magnetic materials found in nature. The demand for the production of these nanoparticles is significantly high due to their exceptional properties. The aim of the present study is to synthesize magnetic nanoparticles of Nd2Fe14B using ethanol in the wet ball milling technique (WBMT).
View Article and Find Full Text PDFMethods
January 2025
School of Computer Science and Engineering, Central South University, Changsha 410083, China; Hunan Provincial Key Lab on Bioinformatics, Central South University, Changsha 410083, China.
Exploring the associations between microbes and drugs offers valuable insights into their underlying mechanisms. Traditional wet lab experiments, while reliable, are often time-consuming and labor-intensive, making computational approaches an attractive alternative. Existing similarity-based machine learning models for predicting microbe-drug associations typically rely on integrated similarities as input, neglecting the unique contributions of individual similarities, which can compromise predictive accuracy.
View Article and Find Full Text PDFEnviron Res
January 2025
Key Lab of Northwest Water Resource, Environment, and Ecology, Ministry of Education, Xi'an University of Architecture and Technology, Xi'an, 710055, China; School of Environmental and Municipal Engineering, Xi'an University of Architecture and Technology, Xi'an, 710055, China.
Controlling runoff pollution is crucial to improving ecological environments in the context of urbanization and climate change. However, a significant research gap remains in the treatment and reuse of roof runoff, particularly during the first flush. To address this, a novel dry-wet polymorphic constructed wetland (DWP-CW) system was developed to purify first flush runoff efficiently and reliably.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Biochemistry, Jawaharlal Nehru Medical College, Faculty of Medicine, Aligarh Muslim University, Aligarh, Uttar Pradesh, India. Electronic address:
Persistence of long-term hyperglycemia results in the glyco-oxidation of plasma proteins, which is considered to be a significant factor in metabolic dysfunction, linking hyperglycemia to the emergence of vascular complications. Methylglyoxal (MGO), a dicarbonyl species formed excessively under diabetes, elevates the oxidative stress, enhancing the generation of superoxide anion, which ultimately reacts with nitric oxide (NO•) to form peroxynitrite (PON). PON, being a powerful nitro-oxidizing agent distorts protein structure, hampering its function.
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