A cationic water-soluble dipicolylamine (DPA)-containing alkynylplatinum(II) terpyridine complex has been synthesized and employed as a dual-selective probe for the detection of cations and anions. The complex was shown to exhibit a strong binding affinity toward Zn, whereas the zinc-bound adduct was found to demonstrate the capability of recognizing pyrophosphate (PPi). As evidenced by molecular modeling and various spectroscopic and spectrometric studies, including HR-ESI mass spectrometry, NMR spectroscopy, PXRD measurements, and UV-vis absorption and emission spectroscopy, a PPi anion was found to be capable of bridging two zinc-bound complex molecules in a clip-shaped fashion, which was further oligomerized through intermolecular Pt···Pt and π-π stacking interactions to form nanofibers with a hexagonal columnar phase. This work provides important insights into not only the construction of aesthetically pleasing supramolecular architectures but also the multifunctional probes, which offer great promise to the fields of biosensing and chemical sensing.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/jacs.0c11162 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Allelic variants in xenobiotic metabolism genes predict susceptibility and worse prognosis of urothelial bladder cancer.
Pathol Res Pract
December 2024
Department of General Biology, Center of Biological Sciences, State University of Londrina (UEL), Londrina 86057-970, Brazil. Electronic address:
Biomarkers that identify tumors with better/worse prognosis can help reduce treatment costs and contribute to patient survival. In urothelial bladder cancer (UBC), accurate prediction of recurrence and progression is essential to inform therapeutic management. Herein, we explore the role of genetic variants of xenobiotic metabolic pathways in UBC susceptibility and prognosis.
View Article and Find Full Text PDFAssociation of Cytotoxic T-Lymphocyte Antigen-4 () Genetic Variants with Risk and Outcome of Cutaneous Melanoma.
Int J Mol Sci
November 2024
Laboratory of Cancer Genetics, School of Medical Sciences, State University of Campinas, Campinas 13083-970, SP, Brazil.
This study aimed to verify whether germline single nucleotide variants (SNV) in gene, c.-1765C>T, c.-1661A>G, c.
View Article and Find Full Text PDFModels of Fluctuating Selection Between Generations: A Solution for the Theoretical Inconsistency.
J Mol Evol
December 2024
Department of Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa, IA, 50011, USA.
Article Synopsis
- The theory of selection fluctuation between generations has been widely discussed in population genetics since the 1970s, highlighting that mutation frequencies may oscillate around 0.5 before becoming fixed or lost.
- The concept of a "reference phenotype" is introduced, which posits that one of the three genotypes (AA, AA', A'A') must retain constant fitness to support fluctuating selection.
- A proposed mixture model suggests that all three genotypes should be considered as potential reference types, revealing that balancing selection emerges based on their relative frequencies.
Aminoacid functionalised magnetite nanoparticles FeO@AA (AA = Ser, Cys, Pro, Trp) as biocompatible magnetite nanoparticles with potential therapeutic applications.
Sci Rep
October 2024
Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, National University of Science and Technology Politehnica Bucharest, 1-7 Gh Polizu Street, 011061, Bucharest, Romania.
Magnetic nanoparticles (MNPs) are of great interest for their wide applications in biomedical applications, such as bioimaging, antitumoral therapies, regenerative medicine, and drug delivery. The work aimed to obtain biocompatible magnetite nanoparticles coated with amino acids of the general formula FeO@AA (AA = L-tryptophan, L-serine, L-proline and L-cysteine) for potential therapeutic application in anticancer drug delivery. The obtained materials were characterised using XRD, FTIR, DLS analysis, SEM, thermogravimetry (TG), differential scanning calorimetry (DSC), and UV-vis spectroscopy.
View Article and Find Full Text PDFA Prospective Comparative Study on the Clinical Diagnostic Performance of Blood Inflammatory Markers in Acute Appendicitis.
J Inflamm Res
October 2024
Department of Clinical Laboratory, People's Hospital of HuiLi City, Huili, Sichuan Province, 615100, People's Republic of China.
Objective: Despite the substantial advancements in imaging techniques for the diagnosis and differential diagnosis of acute appendicitis (AA) over recent decades, the specificity and sensitivity of widely utilized laboratory biomarkers in clinical practice remain inadequate.This study aimed to investigate the diagnostic utility of commonly employed blood inflammatory markers for AA.
Methods: A total of 399 participants who either sought medical care or underwent health examinations were enrolled in this prospective study.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!