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| http://dx.doi.org/10.1186/s13054-020-03437-w | DOI Listing |
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Stability of carboxy-hemoglobin during storage at different temperatures.
Drug Test Anal
May 2024
Division of Sports Medicine/Sports Physiology, University of Bayreuth, Bayreuth, Germany.
Accurate determination of carboxy-hemoglobin (COHb%) is essential for the assessment of hemoglobin mass (Hbmass) by CO-rebreathing. To analyze blood samples for a certain period of time after blood collection, it is necessary to know the stability of the COHb% during storage. The aim of the study was to determine the stability of COHb% at different storage temperatures over a period of up to 3 months.
View Article and Find Full Text PDFDuplicate measures of hemoglobin mass within an hour: feasibility, reliability, and comparison of three devices in supine position.
Scand J Clin Lab Invest
February 2024
Department of Nutrition, Exercise and Sports (NEXS), University of Copenhagen, Copenhagen, Denmark.
Duplicate measure of hemoglobin mass by carbon monoxide (CO)-rebreathing is a logistical challenge as recommendations prompt several hours between measures to minimize CO-accumulation. This study investigated the feasibility and reliability of performing duplicate CO-rebreathing procedures immediately following one another. Additionally, it was evaluated whether the obtained hemoglobin mass from three different CO-rebreathing devices is comparable.
View Article and Find Full Text PDFCarbon monoxide related deaths: A Verona case series. When cooperation becomes compulsory.
Leg Med (Tokyo)
March 2024
Department of Diagnostic and Public Health, Section of Forensic Medicine, University of Verona, P.le L.A. Scuro 10, 37134 Verona, Italy.
Introduction: Carbon monoxide (CO) poisoning is a significant concern in forensic medicine, as it often presents unique challenges in terms of diagnosis, investigation, and determination of the cause of death. CO is a colourless, odourless, and tasteless gas that can be lethal when inhaled in high concentrations. It binds strongly to haemoglobin, forming carboxyhaemoglobin (COHb), which reduces the oxygen-carrying capacity of the blood, leading to tissue hypoxia and ultimately death.
View Article and Find Full Text PDFDiagnostic accuracy of carboxyhemoglobin saturation with pulse CO-oximetry in patients with carbon monoxide poisoning.
Toxicol Res (Camb)
October 2023
Department of Emergency Service, Ankara Dr Abdurrahman Yurtarslan Oncology Training and Research Hospital, University of Health Sciences, Yenimahalle, Ankara, Turkey.
Objective: Carboxyhemoglobin saturation (SpCO)with pulse CO-oximetry is an alternative method in CO poisoning; however, the correlation of it with blood carboxyhemoglobin level (COHb) is still debated.The study aimed to evaluate the correlation between SpCO and venous COHb level and factors associated with the diagnostic accuracy of SpCO.
Material And Methods: SpCO and venous COHb levels of patients with CO poisoning, according to a COHb level was 3%, were evaluated.
Evaluation of a Portable Blood Gas Analyzer for Prehospital Triage in Carbon Monoxide Poisoning: Instrument Validation Study.
JMIR Form Res
October 2023
Division of Emergency Medicine, Department of Anesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland.
Background: Carbon monoxide (CO) poisoning is an important cause of morbidity and mortality worldwide. Symptoms are mostly aspecific, making it hard to identify, and its diagnosis is usually made through blood gas analysis. However, the bulkiness of gas analyzers prevents them from being used at the scene of the incident, thereby leading to the unnecessary transport and admission of many patients.
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