Management of uterine rupture during molar pregnancy.

J Gynecol Obstet Hum Reprod

Service de Gynécologie-Obstétrique, Centre Hospitalier de Versailles, 177 Rue de Versailles, 78150, Le Chesnay-Rocquencourt, France. Electronic address:

Published: September 2021

Gestational trophoblastic disease (GTD) is rare and encompasses several clinicopathologic forms from pre-malignant to malignant disorders. Clinical presentation is most of the time dominated by vaginal bleeding. Only few cases of uterine rupture during GTD have been reported in literature. We present the case of a female patient admitted to the hospital for hemorrhagic shock secondary to a uterine rupture due to an undiagnosed GTD. After an emergency laparoscopy, the patient underwent total hysterectomy with bilateral salpingectomy and bilateral ovarian cystectomy. Pulmonary metastasis were discovered on imaging after stagnation of the beta-hCG level. The surgical treatment was completed by 6 cycles of Methotrexate followed by 7 cycles of Actinomycine D with a good response.

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http://dx.doi.org/10.1016/j.jogoh.2020.102058DOI Listing

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