Ultrasound-guided versus conventional lung recruitment manoeuvres in laparoscopic gynaecological surgery: A randomised controlled trial.

Eur J Anaesthesiol

From the Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea (SKP, HY, SY, WHK, YJL, JHB, JTK).

Published: March 2021

AI Article Synopsis

  • Pneumoperitoneum and steep Trendelenburg position during laparoscopic gynecological surgery can lead to pulmonary atelectasis, prompting a study to see if ultrasound-guided recruitment maneuvers are more effective than conventional techniques in reducing this issue.
  • The study was a randomized controlled trial involving 40 adult patients, with one group receiving ultrasound-guided recruitment and the other conventional recruitment maneuvers during surgery.
  • Results showed that patients in the ultrasound-guided group had significantly better lung ultrasound scores (indicating better lung aeration) both at the end of surgery and in the post-anesthesia care unit, and a lower incidence of atelectasis compared to the control group.

Article Abstract

Background: Pneumoperitoneum and steep Trendelenburg position promote the formation of pulmonary atelectasis during laparoscopic gynaecological surgery.

Objective: To determine whether lung ultrasound-guided alveolar recruitment manoeuvres could reduce peri-operative atelectasis compared with conventional recruitment manoeuvres during laparoscopic gynaecological surgery.

Design: Randomised controlled trial.

Setting: Tertiary hospital, Republic of Korea, from August 2018 to January 2019.

Patients: Adult patients scheduled for laparoscopic gynaecological surgery under general anaesthesia.

Intervention: Forty patients were randomised to receive either ultrasound-guided recruitment manoeuvres (manual inflation until no visibly collapsed area was seen with lung ultrasonography; intervention group) or conventional recruitment manoeuvres (single manual inflation with 30 cmH2O pressure; control group). Recruitment manoeuvres were performed 5 min after induction and at the end of surgery in both groups. All patients received volume-controlled ventilation with a tidal volume of 8 ml kg-1 and a positive end-expiratory pressure of 5 cmH2O.

Main Outcome Measures: The primary outcome was the lung ultrasound score at the end of surgery; a higher score indicates worse lung aeration.

Results: Lung ultrasound scores at the end of surgery were significantly lower in the intervention group compared with control group (median [IQR], 7.5 [6.5 to 8.5] versus 9.5 [8.5 to 13.5]; difference, -2 [95% CI, -4.5 to -1]; P = 0.008). The intergroup difference persisted in the postanaesthesia care unit (7 [5 to 8.8] versus 10 [7.3 to 12.8]; difference, -3 [95% CI, -5.5 to -1.5]; P = 0.005). The incidence of atelectasis was lower in the intervention group compared with control group at the end of surgery (35 versus 80%; P = 0.010) but was comparable in the postanaesthesia care unit (40 versus 55%; P = 0.527).

Conclusions: The use of ultrasound-guided recruitment manoeuvres improves peri-operative lung aeration; these effects may persist in the postanaesthesia care unit. However, the long-term effects of ultrasound-guided recruitment manoeuvres on clinical outcomes should be the subject of future trials.

Trial Registration: ClinicalTrials.gov (NCT03607240).

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Source
http://dx.doi.org/10.1097/EJA.0000000000001435DOI Listing

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