How Useful can the Voigt Profile be in Protein Folding Processes?

Protein J

Baker Laboratory of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, 14853-1301, USA.

Published: April 2021

The analytical expression for the Voigt profile, along with its simplified forms for the Gaussian and Lorentzian dominance, is presented. The applicability of the Voigt profile in the description of anomalous diffusion phenomena, ubiquitous in different fields of science including protein folding, is discussed. It is shown that the Voigt profile is a good descriptor of the processes occurring in protein folding and in the native state. The usefulness of the Voigt profile in deriving important information of the diffusive motions in proteins from a quasielastic incoherent neutron scattering experiments is illustrated.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026557PMC
http://dx.doi.org/10.1007/s10930-020-09954-5DOI Listing

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