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Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways. | LitMetric
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Age-related injury responses of human oligodendrocytes to metabolic insults: link to BCL-2 and autophagy pathways.

Milton Guilherme Forestieri Fernandes Julia Xiao Xuan Luo Qiao-Ling Cui Kelly Perlman Florian Pernin Moein Yaqubi Jeffery A Hall Roy Dudley Myriam Srour Charles P Couturier Kevin Petrecca Catherine Larochelle Luke M Healy Jo Anne Stratton Timothy E Kennedy Jack P Antel

Commun Biol

Neuroimmunology Unit, Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, QC, H3A 2B4, Canada.

Published: January 2021

Myelin destruction and oligodendrocyte (OL) death consequent to metabolic stress is a feature of CNS disorders across the age spectrum. Using cells derived from surgically resected tissue, we demonstrate that young (

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7782481PMC
http://dx.doi.org/10.1038/s42003-020-01557-1DOI Listing

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