The aim of this study was to analyze the characteristics of physical and sexual development of patients with menstrual irregularities while monitoring over the past 20 years. Physical and sexual development of 497 patients with abnormal uterine bleeding (AMC PP) and 677 with hypomenstrual syndrome (HMS) aged 10 to 18 years were evaluated who were treated in the period 1997-2002 and 2010-2016. The data were compared with the results of epidemiological studies of a population of schoolgirls in Kharkov region. Monitoring of physical development of patients with menstrual dysfunction showed a significant deterioration in recent years. In modern girls with menstrual pathology, disharmony of physical development was recorded in almost every second, which is significantly more often than in the population and in relation to patients examined 15-20 years ago (р<0.001-0.0001). Deviations in sexual development were recorded in more than half of patients with menstrual dysfunction. Moreover, its advance was much more often recorded in case of abnormal uterine bleeding at puberty, and lag in hypomenstrual syndrome. Earlier menarche was more characteristic for abnormal uterine bleeding at puberty and later one - at hypomenstrual syndrome. Physical development of girls can be considered as a "marker" of their health status, an indicator of forecast for the formation of reproductive potential and fertility in the future.
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