AI Article Synopsis
- The study analyzed the nasal bacterial microbiota of healthy horses versus those infected with equine herpesvirus 1 (EHV-1) using advanced sequencing technology.
- Horses infected with EHV-1 displayed significantly reduced bacterial richness, evenness, and diversity compared to healthy horses.
- Healthy horses had a higher abundance of certain bacterial groups (Firmicutes and Bacteroidetes) while showing lower levels of Proteobacteria than EHV-1 infected horses, suggesting potential bacterial-viral interactions affecting equine health.
Article Abstract
The objective of this study was to investigate the nasal bacterial microbiota of healthy horses and horses infected with equine herpesvirus 1 (EHV-1). The nasal bacterial microbiota of 10 horses infected with EHV-1 and 11 control horses from a farm experiencing an outbreak was characterized using the Illumina MiSeq platform targeting the V4 region of the 16S ribosomal RNA gene. The nasal bacterial microbiota of healthy horses and EHV-1 horses was significantly different in community membership and structure. Horses shedding EHV-1 had lower bacterial richness ( = 0.002), evenness ( = 0.008), and diversity ( = 0.026) than healthy horses. Healthy horses had a higher relative abundance of Firmicutes and Bacteroidetes, but lower Proteobacteria than horses with EHV-1 ( < 0.05). This study provides the basis for generating hypotheses and investigations on the role of bacterial-viral interactions in the health and diseases of adult horses.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747660 | PMC |
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