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| http://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16623 | DOI Listing |
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How SNARE proteins generate force to fuse membranes.
Biophys J
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Department of Chemical Engineering, Columbia University, New York, NY 10027. Electronic address:
Membrane fusion is central to fundamental cellular processes such as exocytosis, when an intracellular machinery fuses membrane-enclosed vesicles to the plasma membrane for contents release. The core machinery components are the SNARE proteins. SNARE complexation pulls the membranes together, but the fusion mechanism remains unclear.
View Article and Find Full Text PDFA machine learning model the prediction of athlete engagement based on cohesion, passion and mental toughness.
Sci Rep
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View Article and Find Full Text PDFLDPC-cat codes for low-overhead quantum computing in 2D.
Nat Commun
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Université de Lorraine, CNRS, Inria, LORIA, F-54000, Nancy, France.
The main obstacle to large scale quantum computing are the errors present in every physical qubit realization. Correcting these errors requires a large number of additional qubits. Two main avenues to reduce this overhead are (i) low-density parity check (LDPC) codes requiring very few additional qubits to correct errors (ii) cat qubits where bit-flip errors are exponentially suppressed by design.
View Article and Find Full Text PDFPropolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings.
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View Article and Find Full Text PDFRapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy.
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The neuromuscular junction (NMJ) is essential for transmitting signals from motor neurons (MNs) to skeletal muscles (SKMs), and its dysfunction can lead to severe motor disorders. However, our understanding of the NMJ is limited by the absence of accurate human models. Although human induced pluripotent stem cell (iPSC)-derived models have advanced NMJ research, their application is constrained by challenges such as limited differentiation efficiency, lengthy generation times, and cryopreservation difficulties.
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