Since the relatively recent regulatory approval for clinical use in both Europe and North America, 7-Tesla (T) MRI has been adopted for clinical practice at our institution. Based on this experience, this article reviews the unique features of 7-T MRI neuroimaging and addresses the challenges of establishing a 7-T MRI clinical practice. The underlying fundamental physics principals of high-field strength MRI are briefly reviewed. Scanner installation, safety considerations, and artifact mitigation techniques are discussed. Seven-tesla MRI case examples of neurologic diseases including epilepsy, vascular abnormalities, and tumor imaging are presented to illustrate specific applications of 7-T MRI. The advantages of 7-T MRI in conjunction with advanced neuroimaging techniques such as functional MRI are presented. Seven-tesla MRI produces more detailed information and, in some cases, results in specific diagnoses where previous 3-T studies were insufficient. Still, persistent technical issues for 7-T scanning present ongoing challenges for radiologists.
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http://dx.doi.org/10.1007/s00234-020-02629-z | DOI Listing |
Phys Med Biol
January 2025
CNRS, BAOBAB, CEA, NeuroSpin, Université Paris-Saclay, Gif-sur-Yvette, 91191, FRANCE.
Ultra-high field MRI with parallel transmission (pTx) provides a powerful neuroimaging tool with potential application in paediatrics. The use of pTx, however, necessitates a dedicated local specific absorption rate (SAR) management strategy, able to predict and monitor the peak local SAR (pSAR). In this work, we address the pSARassessment for an in-house built 7 Tesla 16Tx32Rx pediatric head coil, using the concept of Virtual Observation Points (VOPs) for SAR estimation.
View Article and Find Full Text PDFMol Imaging Biol
January 2025
Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Purpose: Proton exchange rate (K) is a valuable biophysical metric. K MRI may augment conventional structural MRI by revealing brain impairments at the molecular level. This study aimed to investigate the feasibility of K MRI in evaluating brain injuries at multiple epilepsy stages.
View Article and Find Full Text PDFFront Vet Sci
December 2024
Department of Ophthalmology, Rostock University Medical Center, Rostock, Germany.
Introduction: The chicken egg, with its compartments, is a widely used and popular animal model in experimental studies. This study aimed to quantify the volumes of the yolk/yolk sac, amniotic fluid, and chicken embryo using non-invasive ultra-high-field magnetic resonance imaging (UHF-MRI).
Materials And Methods: In total, 64 chicken eggs were examined using a 7 T UHF-MRI scanner, acquiring T2-weighted anatomical images of the entire egg from developmental day 1 to 16 (D1-D16).
Phenomics
October 2024
Human Phenome Institute, Institute of Medical Genetics and Genomics, MOE Key Laboratory of Contemporary Anthropology, Zhangjiang Fudan International Innovation Center, Fudan University, 825 Zhangheng Road, Shanghai, 201203 China.
Unlabelled: () is a neuro-specific gene linked to neurodevelopmental disorders and has recently been reported to function as a bidirectional emotional regulator, highlighting its molecular roles in the nervous system. However, the connections between , brain architecture, and functionality remain to be fully elucidated. Our study utilized 11.
View Article and Find Full Text PDFEur J Neurol
January 2025
Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Background: A dual-syndrome hypothesis, which states the cognitive impairments in Parkinson's disease (PD) are attributable to frontostriatal dopaminergic dysregulation and cortical disturbance-each associated with attention/executive and memory/visuospatial dysfunction, respectively-has been widely accepted. This multisystem contribution also underlies highly heterogeneous progression rate to dementia.
Methods: Nondemented PD patients who underwent [I]N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane ([I]FP-CIT) SPECT and neuropsychological examinations were enrolled.
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