Fricke gel dosimetry is a valuable technique used for recording 3D dose distribution in radiotherapy. Herein, we present the dosimetric characteristics of a synthesized ferrous-agarose-xylenol orange gel dosimeter in a clinical Co beam. Experimental data were obtained using a secondary standards dosimetry laboratory Co therapy unit. The dosimeter was calibrated using the ionization chamber as a reference, and its total mass attenuation coefficient, absorption spectrum, optical density-dose relationship, sensitivity, and dose rate dependency were evaluated. The potentiality of the ferrous-agarose-xylenol gel dosimeter was investigated to measure output factors for different field sizes. The gel dosimeter readings were measured using a spectrophotometer. The ferrous-agarose-xylenol gel dosimeter exhibited a linearity in the range of 3-15 Gy, indicating that the dosimeter is tissue-equivalent and dose rate-independent and yield reproducible results. The measured output factors and those published in the literature showed good agreement.
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http://dx.doi.org/10.1007/s12194-020-00600-4 | DOI Listing |
Appl Radiat Isot
December 2024
Radiation Application Research School, Nuclear Science and Technology Research Institute, Tehran, Iran.
A gamma cell unit is used for gamma irradiation of small volume samples. Due to the sample volume, there is a dose distribution, which is imperative to be known for appropriate irradiation. In this study, samples of agarose Fricke gel dosimeters were prepared for the dose mapping of the gamma cell unit available in our laboratory.
View Article and Find Full Text PDFPhys Imaging Radiat Oncol
October 2024
Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands.
Background And Purpose: During an end-to-end (E2E) test on the online workflow of the MR-linac, the performance of the treatment starting from the acquisition of pre-treatment MRI scans and ending with dose delivery is quantified. In such a test, the geometrical accuracy of the entire workflow is assessed. Ideally, the 3D geometrical accuracy of dose delivery on an MR-linac should be assessed using dosimeters that provide 3D dose distributions.
View Article and Find Full Text PDFMed Phys
October 2024
Department of Radiation Oncology, National Cancer Center Hospital East, Chiba, Japan.
Background: Comprehensive quality assurance (QA) for a seamless workflow of high-dose-rate brachytherapy, from imaging to planning and irradiation, is uncommon, and QA of the source dwell position is performed in one- or two-dimensions. Gel dosimetry using magnetic resonance imaging (MRI) is effective in verifying the three-dimensional distribution of doses for image-guided brachytherapy (IGBT). However, MRI scanners are not readily accessible, and MRI scanning is time-consuming.
View Article and Find Full Text PDFFree Radic Biol Med
November 2024
Department of Radiology, Gifu University, Gifu, Japan; Innovation Research Center for Quantum Medicine, Gifu University, Gifu, Japan; Department of Radiology, Frontier Science for Imaging, School of Medicine, Gifu University, Gifu, Japan.
The dose of X-ray irradiation is commonly measured by point assessment with an ionization chamber dosimeter. However, to achieve spatially accurate delivery of X-ray to avoid the exposure to normal tissues, an accurate imaging method for spatially and quantitatively detecting exposure is required. Herein, we present a novel method to visualize X-ray exposure using low-field dynamic nuclear polarization magnetic resonance imaging (DNP-MRI) with nitroxyl radical tempol as the chemical dosimeter.
View Article and Find Full Text PDFMed Phys
January 2025
Toshiba Energy Systems & Solutions Corporation, Kawasaki, Japan.
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