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Differential serological and neutralizing antibody dynamics after an infection by a single SARS-CoV-2 strain. | LitMetric

Background: We report here the case of two coworkers infected by the same SARS-CoV-2 strain, presenting two different immunological outcomes.

Case: One patient presented a strong IgG anti-receptor-binding domain immune response correlated with a low and rapidly decreasing titer of neutralizing antibodies. The other patient had a similar strong IgG anti-receptor-binding domain immune response but high neutralizing antibody titers.

Discussion And Conclusion: Thus, host individual factors may be the main drivers of the immune response varying with age and clinical severity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7776280PMC
http://dx.doi.org/10.1007/s15010-020-01556-8DOI Listing

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