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[F]FDG PET/CT Beyond Staging: Prognostic Significance of Sarcopenia and Adipose Tissue Metabolism in Esophageal Carcinoma.
Rev Esp Med Nucl Imagen Mol (Engl Ed)
December 2024
Department of Radiology, University of Health Sciences, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Turkey.
Aim: This study aimed to investigate the relationship between PET and CT parameters and sarcopenia, adipose tissue, and tumor metabolism in esophageal carcinoma(EC) and its impact on survival in EC.
Method: Our study included 122 EC patients who underwent PET/CT for staging. Muscle and adipose tissue characteristics were evaluated, including lumbar(L3) and cervical(C3) muscle areas, psoas major(PM) and sternocleidomastoid muscle(SCM) parameters, and PET parameters for visceral and subcutaneous adipose tissue(SAT).
[Analysis of the effectiveness of cataract surgery in neovascular age-related macular degeneration].
Vestn Oftalmol
December 2024
Novosibirsk State Regional Hospital, Novosibirsk, Russia.
Purpose: This study evaluated the impact of phacoemulsification cataract surgery (PE) on anatomical and functional parameters, as well as the regimen and frequency of anti-VEGF injections in patients with neovascular age-related macular degeneration (nAMD) over a long-term period (up to 3 years).
Material And Methods: The study included 117 patients (117 eyes) diagnosed with nAMD and cataract, graded by LOCS: LOCS I (=56; 47.9%), LOCS II (=57; 48.
Impact of enzyme replacement therapy on clinical manifestations in females with Fabry disease.
Orphanet J Rare Dis
December 2024
Department of Internal Medicine D, and Interdisciplinary Fabry Center (IFAZ), University Hospital Muenster, Muenster, Germany.
Background: The aim of our multicenter study was to investigate the implementation of the European Fabry guidelines on therapeutic recommendations in female patients with Fabry disease (FD) and to analyze the impact of enzyme replacement therapy (ERT) in treated and untreated females.
Results: Data from 3 consecutive visits of 159 female FD patients from 6 Fabry centers were retrospectively analyzed. According to their treatment, patients were separated in 3 groups (untreated, n = 71; newly ERT-treated, n = 47; long-term ERT-treated, n = 41).
Correction method of Mohr-Coulomb strength criterion for rock based on freeze-thaw and residual effects.
Sci Rep
December 2024
Department of Mechanics, Xi'an University of Science and Technology, Xi'an, 710054, China.
Under confining pressure, rocks transition from brittle failure to plastic failure, and residual strength exists after complete failure. However, in the process of establishing rock damage constitutive models, the strength criteria used usually do not consider residual stress. In cold region engineering, the freeze-thaw effect caused by temperature changes should be considered in the constitutive model, and strength criteria should also be introduced.
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