AI Article Synopsis
- Researchers isolated five new polyoxygenated -cyclohexene derivatives from flower and leaf extracts, named desmoscochinchinenes A-E, along with 11 known compounds.
- The structures of these new compounds were determined using various spectroscopic methods, including UV, IR, NMR, and HRESITOFMS.
- Some of the isolated compounds demonstrated strong -glucosidase inhibitory activities, outperforming the standard control acarbose, with specific IC values indicating their effectiveness.
Article Abstract
Phytochemical investigations from the flower and leaf extracts of resulted in the isolation and structural elucidation of five new polyoxygenated -cyclohexene derivatives, desmoscochinchinenes A-E (-), together with 11 known compounds (-). The structures on the new compounds were elucidated from their spectroscopic data, including UV, IR, NMR, and HRESITOFMS. Some of the isolated compounds were evaluated for their -glucosidase inhibitory activities. Chrysin (), pinocembrin 7--benzoate (), and (-)-(5)-desmoscochinoxepinone B () inhibited -glucosidase better than the standard control (acarbose, IC = 83.5 μM) with IC values of 5.7, 33.8, 53.3 μM, respectively.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772550 | PMC |
| http://dx.doi.org/10.1016/j.heliyon.2020.e05791 | DOI Listing |
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