Background: Mucormycosis is a rare fungal infection affecting immunocompromised patients, with the rhinocerebral variant as the most common presentation. Garcin syndrome is the progressive involvement of the cranial nerves resulting in total unilateral paralysis of cranial nerves, absence of sensory or motor deficits, and not associated with features of raised intracranial pressure. We report a case of invasive rhinocerebral mucormycosis presenting as Garcin syndrome and acute ischemic stroke.
How To Cite This Article: Nagendra V, Thakkar KD, Prasad Hrishi A, Prathapadas U. A Rare Case of Rhinocerebral Mucormycosis Presenting as Garcin Syndrome and Acute Ischemic Stroke. Indian J Crit Care Med 2020;24(11):1137-1138.
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http://dx.doi.org/10.5005/jp-journals-10071-23643 | DOI Listing |
Intern Med
November 2024
Department of Rheumatology, Hamanomachi Hospital, Japan.
A 72-year-old Japanese woman presented to our hospital with progressive hearing loss and dysphagia. Blood tests revealed elevated C-reactive protein and myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA). Contrast-enhanced magnetic resonance imaging of the head showed hypertrophic pachymeningitis of the left middle cranial fossa with compression of the cranial nerves, including the trigeminal (V), facial (VII), glossopharyngeal (IX), and vagal (X) nerves, resulting in cranial nerve palsy.
View Article and Find Full Text PDFCureus
September 2024
Department of Surgery, Baghdad Teaching Hospital, Medical City Complex, Baghdad, IRQ.
Garcin syndrome is a rare neurological condition characterized by progressive unilateral involvement of multiple cranial nerves, without typical intracranial hypertension. It is often linked with aggressive malignancies and invasive infections; hence, it presents significant diagnostic and therapeutic challenges. Despite the advances in medical technology, the prognosis still remains poor, and there is limited literature on comprehensive reviews regarding its etiology, diagnosis, and management.
View Article and Find Full Text PDFJ Fr Ophtalmol
November 2024
Ophthalmology Department, University Hospital of Saint-Étienne, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France; Laboratory Biology, Engineering and Imaging for Ophthalmology, BiiO, EA2521, Federative Institute of Research in Sciences and Health Engineering, Faculty of Medicine, Jean-Monnet University, Saint-Étienne, France; Ophthalmology department 5, hôpital national des 15-20, 28, rue Charenton, 75571 Paris, France. Electronic address:
Rev Neurol (Paris)
March 2024
Service de neurologie, Sorbonne Paris Nord, hôpitaux universitaires de Paris - Seine Saint Denis, hôpital Avicenne, AP-HP, Bobigny, France; Inserm U1050, CNRS UMR7241, Dynamics and Pathophysiology of Neuronal Networks Team, collège de France, Center for Interdisciplinary Research in Biology, université PSL, 75005 Paris, France.
IDCases
June 2023
Otorhinolaryngology Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Garcin syndrome is characterized by progressive unilateral multiple cranial nerve palsy without the presence of intracranial hypertension. In this case, we present a patient who experienced lower cranial nerve (CN 9-12) involvement attributed to post-mucormycosis osteomyelitis of the skull base. The osteomyelitis resulting from mucormycosis led to the development of Garcin syndrome, which manifested as progressive paralysis of the cranial nerves.
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