The role of SGLT-2 inhibitors in managing type 2 diabetes.

Cleve Clin J Med

Director, East Region, Department of Endocrinology Diabetes, and Metabolism, Cleveland Clinic; Assistant Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH

Published: January 2021

AI Article Synopsis

  • - SGLT-2 inhibitors are a type of medication that can significantly benefit patients with type 2 diabetes, not just by lowering blood sugar levels but also through other health improvements.
  • - These drugs have been shown to enhance heart and kidney health, which is crucial since people with type 2 diabetes are at a greater risk for heart and kidney problems.
  • - Ongoing research may lead to even more uses for SGLT-2 inhibitors, as clinical trials continue to explore their full potential.

Article Abstract

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors are an exceptionally versatile class of medication, and their glycemic and nonglycemic benefits could help millions of patients with type 2 diabetes. Of note, they have been shown to improve cardiac and renal outcomes, much-needed benefits in patients with type 2 diabetes, who are at a higher risk for developing cardiac and renal dysfunction than those who do not have diabetes. The indications for SGLT-2 inhibitors may continue to expand as ongoing clinical trials provide more insight into these drugs.

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Source
http://dx.doi.org/10.3949/ccjm.88a.20088DOI Listing

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