COVID-19 is not well studied in Africa. Understanding the clinical profile and management of COVID-19 will help to plan better prevention and treatment strategies taking the local context into consideration. In this study, we described the clinical profile, treatment used, and outcomes of COVID-19 patients in one of the COVID-19 treatment centers of Ethiopia, Boru Meda Hospital. An institution-based retrospective cross-sectional study was carried out using medical records of COVID-19 patients who were admitted to Boru Meda Hospital with a positive reverse transcription (RT)-PCR result from May 9, 2020 to September 20, 2020. All patients with a positive RT-PCR were admitted to the hospital, regardless of symptom and severity status. A total of 279 COVID-19 patients were included in the final analysis. The median age of patients was 28 years (interquartile range 23-40). The majority (69.5%) were male. Around a quarter (n = 73; 26.2%) of the patients were symptomatic, of which cough (n = 49; 67.1%) and fever (n = 32; 43.8%) were common symptoms. Among symptomatic patients, 48 (65.8%) were mild, four (5.5%) moderate, 12 (16.4%) severe, and nine (12.3%) were critical. The case fatality rate was 2.1%. Hypertension, age older than 25 years, and HIV/AIDS were significantly associated with symptomatic infection. In this study, most of the COVID-19 patients were asymptomatic. However, the proportion of severe and critical patients among those with symptoms was high. More studies are needed to assess the effect of HIV/AIDS on the severity and mortality of COVID-19.
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http://dx.doi.org/10.4269/ajtmh.20-1356 | DOI Listing |
Nord J Psychiatry
December 2024
Department of Psychiatry, Psychiatric Centre Copenhagen, Copenhagen, Denmark.
Background: Reliable gender-sensitive normative data is needed to facilitate mental health research and clinical utility of commonly used symptoms scales. This study establishes Danish gender-stratified norms for the 53-item and 18-item Brief Symptom Inventory (BSI-53, BSI-18), proposed attention deficit hyperactivity disorder (ADHD) symptomatology scales from the BSI-53, and the 10-item Symptom Checklist (SCL-10). This study also examines gender-differences in symptom reporting of the ADHD and SCL-10 scales, and assesses potential bias in recent SCL-10 norms.
View Article and Find Full Text PDFCrit Care
December 2024
Department of Critical Care Medicine, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan.
Background: Medical advances in intensive care units (ICUs) have resulted in the emergence of a new patient population-those who survive the initial acute phase of critical illness, but require prolonged ICU stays and develop chronic critical symptoms. This condition, often termed Persistent Critical Illness (PerCI) or Chronic Critical Illness (CCI), remains poorly understood and inconsistently reported across studies, resulting in a lack of clinical practice use. This scoping review aims to systematically review and synthesize the existing literature on PerCI/CCI, with a focus on definitions, epidemiology, and outcomes for its translation to clinical practice.
View Article and Find Full Text PDFBMC Cardiovasc Disord
December 2024
School of Psychology, University of Southampton, Southampton, UK.
Background: Blood pressure (BP) control following stroke is important but currently sub-optimal. This trial aimed to determine whether self-monitoring of hypertension with telemonitoring and a treatment escalation protocol, results in lower BP than usual care in people with previous stroke or transient ischaemic attack (TIA).
Methods: Unblinded randomised controlled trial, comparing a BP telemonitoring-based intervention with control (usual care) for hypertension management in 12 primary care practices in England.
BMC Cancer
December 2024
Department of Data Science, Faculty of Interdisciplinary Science and Technology, Tarbiat Modares University, Tehran, Iran.
Glioblastoma Multiforme (GBM), classified as a grade IV glioma by the World Health Organization (WHO), is a prevalent and notably aggressive form of brain tumor derived from glial cells. It stands as one of the most severe forms of primary brain cancer in humans. The median survival time of GBM patients is only 12-15 months, making it the most lethal type of brain tumor.
View Article and Find Full Text PDFBMC Public Health
December 2024
Independent Researcher, Ho Chi Minh, 727300, Vietnam.
Background: The mental health of Chinese international student returnees is a critical concern impacting their well-being and successful reintegration into home society, especially in the post-COVID-19 era. This study examines how beliefs about changing living conditions, emigration intentions, and belief in fate influence depression levels among these returnees.
Methods: A cross-sectional survey collected data from 1,014 returnees through WeChat public groups.
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