AI Article Synopsis

  • The study reviews the effectiveness of multifocal visual evoked potential (mfVEP) testing for patients with optic neuritis (ON) and multiple sclerosis (MS).
  • It highlights that mfVEP can detect abnormalities and track lesion progression, such as remyelination and atrophy, in these patients.
  • The mfVEP results show strong correlation with other diagnostic tests, suggesting it could help predict the likelihood of developing MS in patients with ON.

Article Abstract

Purpose: To review the evidence on the usefulness of the multifocal visual evoked potential (mfVEP) test in patients with optic neuritis (ON) and/or multiple sclerosis (MS).

Methods: We critically review key published evidence on the use of mfVEP in ON/MS patients and its association with other functional and structural tests.

Results: Multifocal VEP tests are useful in detecting abnormality in patients with ON/MS and monitor the progression of lesions (remyelination, atrophy). In addition, mfVEP has good correlation with conventional visual evoked potential (VEP), standard automated perimetry, optical coherence tomography and magnetic resonance imaging. In patients with ON, mfVEP might be useful in predicting the risk of conversion to MS.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8116218PMC
http://dx.doi.org/10.1007/s10633-020-09799-4DOI Listing

Publication Analysis

Top Keywords

visual evoked
12
multifocal visual
8
patients optic
8
optic neuritis
8
multiple sclerosis
8
evoked potential
8
patients
5
contribution multifocal
4
evoked potentials
4
potentials patients
4

Similar Publications

Visual cues of respiratory contagion: Their impact on neuroimmune activation and mucosal immune responses in humans.

Brain Behav Immun

January 2025

Department of Biology, Neuroendocrinology and Human Biology Unit, Institute for Animal Cell- and Systems Biology, Faculty of Mathematics, Informatics and Natural Sciences, Universität Hamburg, D-22085 Hamburg, Germany. Electronic address:

This study investigated the neural correlates of perceiving visual contagion cues characteristic of respiratory infections through functional magnetic resonance imaging (fMRI). Sixty-two participants (32f/ 30 m; ∼25 years on average) watched short videos depicting either contagious or non-contagious everyday situations, while their brain activation was continuously measured. We further measured the release of secretory immunoglobulin A (sIgA) in saliva to examine the first-line defensive response of the mucosal immune system.

View Article and Find Full Text PDF

Mapping the myomagnetic field of a straight and easily accessible muscle after electrical stimulation using triaxial optically pumped magnetometers (OPMs) to assess potential benefits for magnetomyography (MMG). Approach: Six triaxial OPMs were arranged in two rows with three sensors each along the abductor digiti minimi (ADM) muscle. The upper row of sensors was inclined by 45° with respect to the lower row and all sensors were aligned closely to the skin surface without direct contact.

View Article and Find Full Text PDF

Cerebrospinal fluid (CSF) dynamics, driven by sensory stimulation-induced neuronal activity, is crucial for maintaining homeostasis and clearing metabolic waste. However, it remains unclear whether such CSF flow is impaired in age-related neurodegenerative diseases of the visual system. This study addresses this gap by examining CSF flow during visual stimulation in glaucoma patients and healthy older adults using functional magnetic resonance imaging.

View Article and Find Full Text PDF

Emotional experiences involve dynamic multisensory perception, yet most EEG research uses unimodal stimuli such as naturalistic scene photographs. Recent research suggests that realistic emotional videos reliably reduce the amplitude of a steady-state visual evoked potential (ssVEP) elicited by a flickering border. Here, we examine the extent to which this video-ssVEP measure compares with the well-established Late Positive Potential (LPP) that is reliably larger for emotional relative to neutral scenes.

View Article and Find Full Text PDF

Functional magnetic resonance imaging (fMRI) has dramatically advanced non-invasive human brain mapping and decoding. Functional near-infrared spectroscopy (fNIRS) and high-density diffuse optical tomography (HD-DOT) non-invasively measure blood oxygen fluctuations related to brain activity, like fMRI, at the brain surface, using more-lightweight equipment that circumvents ergonomic and logistical limitations of fMRI. HD-DOT grids have smaller inter-optode spacing (~ 13 mm) than sparse fNIRS (~ 30 mm) and therefore provide higher image quality, with spatial resolution ~ 1/2 that of fMRI, when using the several source-detector distances (13-40 mm) afforded by the HD-DOT grid.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!