The effect of permeability heterogeneities and viscosity variations on miscible displacement processes in porous media is examined using high-resolution numerical simulations and reduced theoretical modelling. The planar injection of one fluid into a fluid-saturated, two-dimensional porous medium with a permeability that varies perpendicular to the flow direction is studied. Three cases are considered, in which the injected fluid is equally viscous, more viscous or less viscous than the ambient fluid. In general it is found that the flow in each case evolves through three regimes. At early times, the flow exhibits the concentration evolves diffusively, independent of both the permeability structure and the viscosity ratio. At intermediate times, the flow exhibits different dynamics including channelling and fingering, depending on whether the injected fluid is more or less viscous than the ambient fluid, and depending on the relative magnitude of the viscosity and permeability variations. Finally, at late times, the flow becomes independent of the viscosity ratio and dominated by shear-enhanced (Taylor) dispersion. For each of the regimes identified above, we develop reduced-order models for the evolution of the transversely averaged concentration and compare them to the full numerical simulations.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7722355 | PMC |
http://dx.doi.org/10.1017/jfm.2019.190 | DOI Listing |
J Magn Reson Imaging
January 2025
Department of Radiology, Endeavor Health, Evanston, Illinois, USA.
Background: Luminal and hemodynamic evaluations of the cervical arteries inform the diagnosis and management of patients with cervical arterial disease.
Purpose: To demonstrate a 3D nonenhanced quantitative quiescent interval slice-selective (qQISS) magnetic resonance angiographic (MRA) strategy that provides simultaneous hemodynamic and luminal evaluation of the cervical arteries.
Study Type: Prospective.
J Cancer
January 2025
Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu 214122, China.
Developing new drug delivery systems is crucial for enhancing the efficacy of oncolytic virus (OV) therapies in cancer treatment. In this study, mesenchymal stem cell (MSC)-derived vesicles and oncolytic viruses are exploited to construct a novel formulation. It has been hypothesized that vesicle-coated OVs could amplify cytotoxic effects through superior internalization by tumor cells.
View Article and Find Full Text PDFCureus
December 2024
Department of Surgery, Tokyo Saiseikai Central Hospital, Tokyo, JPN.
Ectopic varices can result from portal vein stenosis following pancreaticoduodenectomy with concomitant portal vein resection reconstruction, and they can cause gastrointestinal bleeding. Although they can sometimes be fatal, various treatments have been reported. This report describes a case in which a percutaneous transhepatic approach was used to simultaneously perform variceal embolization and portal vein stenting in which a favorable outcome was achieved.
View Article and Find Full Text PDFBiomed Eng Lett
January 2025
Department of Biomedical Engineering, Seoul National University College of Medicine, 103 Daehak-ro, Jongno- gu, Seoul, 03080 Republic of Korea.
Unlabelled: With the advent of robot-assisted surgery, user-friendly technologies have been applied to the da Vinci surgical system (dVSS), and their efficacy has been validated in worldwide surgical fields. However, further improvements are required to the traditional manipulation methods, which cannot control an endoscope and surgical instruments simultaneously. This study proposes a speech recognition control interface (SRCI) for controlling the endoscope via speech commands while manipulating surgical instruments to replace the traditional method.
View Article and Find Full Text PDFJ Phys Chem Lett
January 2025
School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, People's Republic of China.
Efficient capture of single-stranded DNA (ssDNA) is crucial for high-throughput sequencing, which influences the speed and accuracy of genetic analysis. Electrophoresis (EP) and electro-osmotic flow (EOF) have a significant impact on the translocation behavior of ssDNA through the nanopore. Experimentally, dynamically tracking these two effects remains challenging, and conventional numerical methods also struggle to capture their dynamic properties in the presence of DNA.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!