Influenza is viral acute respiratory illness. During winter season flu occurs in local epidemics of various magnitude. Influenza causes substantial loss of workdays, human suffering, and significant mortality rate in population, despite the existing treat ment and effective vaccination.
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Differences in clinical characteristics between coronavirus disease 2019 (COVID-19) and influenza: a systematic review and meta-analysis.
NPJ Prim Care Respir Med
January 2025
Department of Orthopaedics, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
The coronavirus disease 2019 (COVID-19) epidemic has brought major challenges to the global health system, and influenza is also a problem that cannot be ignored. We aimed to explore and compare the clinical characteristics of COVID-19 and influenza to deepen the understanding of these two diseases and provide some guidance for clinicians to make differential diagnoses. We searched PubMed, Embase and Web of Science for articles and performed a meta-analysis using Stata 14.
View Article and Find Full Text PDFIntroduction: Interventions aimed at preventing and treating maternal infections during the gestational period are of paramount importance. Timely immunizations, screening strategies and management of maternal infections reduce the risk of complications for the developing fetus and play a pivotal role in improving neonatal outcomes.
Summary: We summarize evidence for a total of thirteen interventions, pertaining to the prevention and treatment of maternal infections during the antenatal period, from Every Newborn Series published in The Lancet 2014.
Distinct evolution patterns of influenza viruses and implications for vaccine development.
Innovation (Camb)
January 2025
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong (HKU), Hong Kong SAR, China.
In conclusion, the distinct evolution patterns of panzootic influenza A(H5Nx) compared to A(H1N1) and A(H3N2) complicate vaccine development. Effective strategies must consider these unique patterns and the impact of pre-existing immunity. Leveraging AI-based methods for optimized antigen design is essential to mitigate the potential impact of emerging antigenically variable strains and will provide valuable insights for developing more effective vaccines to prepare for future pandemics.
View Article and Find Full Text PDFVV-ECMO adjuvant therapy for complicated with H1N1 infection: a case report.
Front Med (Lausanne)
January 2025
Department of Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Clinical Research Center for Critical Care Medicine, Guangxi, China.
Background: Leptospirosis is an acute infectious disease that occurs by infection, progresses rapidly, and has a high mortality rate, with an estimated 1.2 million new cases and nearly 59,000 deaths each year. Due to its diverse clinical manifestations, diagnosis is often delayed.
View Article and Find Full Text PDFThe WHO Disease Outbreak News during the Covid-19 pandemic.
PLOS Glob Public Health
January 2025
Center for Global Health Science and Security, Georgetown University Medical Center, Washington, DC, United States of America.
During the Covid-19 pandemic, the World Health Organization (WHO) was an important public source of information - not only about the pandemic, but also thousands of other potential health emergencies. Here, we examine the 242 reports published in the WHO Disease Outbreak News (DON) during the first four years of the Covid-19 pandemic (2020 to 2023), and document the diseases and regions that were reported. We find that multinational epidemics of diseases like Ebola virus and MERS-CoV continue to dominate the DON.
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