Gut microbiota is closely related to health and diseases as well as a frontier subject in medical research. Lots of studies have shown a close relationship of gut microbiota with the risk factors for ED, such as stress, anxiety, hormonal disorders, obesity, diabetes mellitus, and thyroid hormones. This review focuses on the correlation between gut microbiota and ED in the aspects of mental psychology, neurotransmitters, vascular endothelium, androgen and thyroid function, hoping to provide a new research direction for the pathogenesis and treatment of ED.
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January 2025
Faculty of Pharmacy and Medical Sciences, University of Petra, Amman, 11196, Jordan.
Prebiotics, traditionally linked to gut health, are increasingly recognized for their systemic benefits, influencing multiple organ systems through interactions with the gut microbiota. Compounds like inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS) enhance short-chain fatty acid (SCFA) production, benefiting neurocognitive health, cardiovascular function, immune modulation, and skin integrity. Advances in biotechnology, including deep eutectic solvents (DES) for extraction and machine learning (ML) for personalized formulations, have expanded prebiotic applications.
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mBio
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Centre for Microbiology and Environmental Systems Science, Department of Microbiology and Ecosystem Science, Division of Microbial Ecology, University of Vienna, Vienna, Austria.
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