Background: Streptococcus pneumonia is a cause of serious mortality and morbidity, especially among small children. However, currently, it causes lower rates of invasive infections due to successful vaccination programs Case. We report an exceptional case of a 6-month-old child with meningoencephalitis caused by Streptococcus pneumonia despite the administration of two doses of pneumococcal conjugate vaccine (PCV). Meningitis progressed rapidly and led to widespread damage in parenchymal brain tissue with the emergence of fulminant meningoencephalitis. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed widespread brain lesions, suggesting extensive parenchymal injury.
Conclusion: Such diffuse white matter lesions among pediatric patients with Streptococcus pneumonia meningoencephalitis despite two doses of PCV have not been reported previously.
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http://dx.doi.org/10.24953/turkjped.2020.06.018 | DOI Listing |
Qual Life Res
January 2025
MRL, Merck & Co., Inc., Rahway, NJ, USA.
Purpose: Cost-utility analyses examining the value of new vaccines for pneumococcal disease will require health state utilities as inputs. Existing utilities for pneumococcal infections in young children are limited. The purpose of this study was to estimate health state utilities associated with pneumococcal infections in young children.
View Article and Find Full Text PDFMucosal Immunol
December 2024
Department of Infectious Diseases, Respiratory Medicine and Critical Care, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; German center for lung research (DZL), Augustenburger Platz 1, 13353 Berlin, Germany. Electronic address:
Diabetes mellitus is associated with an increased risk of pneumonia, often caused by so-called typical and atypical pathogens including Streptoccocus pneumoniae and Legionella pneumophila, respectively. Here, we employed a variety of mouse models to investigate how diabetes influences pulmonary antibacterial immunity. Following intranasal infection with S.
View Article and Find Full Text PDFCureus
December 2024
Neurosurgery, Nagoya University Hospital, Nagoya, JPN.
Austrian syndrome is a rare triad of meningitis, pneumonia, and endocarditis caused by . It is associated with high morbidity and mortality rates. Most reports describe pneumonia as the initial illness, followed by multi-organ involvement.
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November 2024
Department of Internal Medicine, School of Medicine, Ibb University, Ibb, YEM.
Background: Acute bacterial meningitis (ABM) is a significant public health problem in developing countries, including Yemen, especially during warfare. This is because persistent political turmoil impedes ABM prevalence, etiology, and treatment. Here, we investigate the factors associated with mortality among hospitalized children with ABM in a resource-limited setting.
View Article and Find Full Text PDFCureus
December 2024
Critical Care, Unidade Local de Saúde de Braga, Braga, PRT.
Community-acquired pneumonia (CAP) varies in clinical presentation, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis. We present a 40-year-old woman who presents to the emergency room with dyspnea, pleuritic chest pain, productive cough with hemoptysis, and fever. On physical examination, the patient presents with tachypnea and hypotension, which proved refractory to fluid therapy.
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