AI Article Synopsis
Article Abstract
Punicic acid (PA) is a polyunsaturated fatty acid (18:3 n-5), which is classified as a conjugated linolenic acid. PA is also referred as a "super CLnA" whose effect is even more potent than that of an ordinary CLnA. It is found mainly in the seeds of pomegranate fruit (Punica granatum) and Trichoxanthes kirilowii and some other minor sources. It possesses a wide array of biological properties including antidiabetic, antiobesity, antiproliferative, and anticarcinogenic activity against various forms of cancer. In spite of this, PA has not been explored as a nutraceutical or as an ingredient of food products which can be aimed at specific consumer target groups. This review details the various health-beneficial properties of PA and explores the possibilities of its utilization as an active ingredient in various food products.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/1541-4337.12171 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Determination of main lipids and volatile compounds in unconventional cold-pressed seed oils through chromatographic techniques.
J Food Sci
January 2025
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, Messina Institute of Technology, University of Messina, Messina, Italy.
The purpose of this study was to characterize unconventional cold-pressed seed oils (rosehip, strawberry, blackcurrant, carrot, plum, pomegranate, radish, and raspberry) as novel alternative edible oil source. A chemical characterization of different lipid components (total fatty acid composition, triacylglycerols, and vitamin E) and volatiles responsible for the particular aroma of these oils was reported. All the oils showed a content of unsaturated fatty acids, mainly oleic, linoleic, and α-linolenic acid, that potentially contribute to the prevention of cardiovascular diseases, in the range of 80%-90%.
View Article and Find Full Text PDFEfficacy and safety of a proprietary extract in skin health - a randomized, placebo-controlled clinical study in healthy volunteers.
Am J Transl Res
December 2024
Trial Guna Private Limited 476, JP Nagar, Bangalore 560083, India.
Objectives: The concept of beauty from within is a growing trend in the market and people now look for oral supplements that can enhance the well-being of skin from within. Within this principle, a proprietary pomegranate extract (Grantria), standardized to ellagic acid, punicic acid and punicalagin, was developed using ADOP (Advanced Oil-Powder) technology and was clinically evaluated for its efficacy and safety in healthy adults.
Methods: This evaluation was carried out as a randomized, placebo-controlled clinical study for 60 days at a daily dose of 300 mg.
Microplate spectrophotometric method for regioselective lipase screening using structured triglycerides with punicic acid as probe.
Anal Biochem
January 2025
Biotecnología Industrial, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, CIATEJ, 45019, Zapopan, Jalisco, Mexico. Electronic address:
In this study, we propose a continuous assay that provides a high-throughput, efficient method for screening the regioselectivity of lipases at the sn-1,3 and sn-2 positions on triacylglycerols (TAGs). This assay measures the specific hydrolysis rates at the primary and secondary positions of TAGs derivates containing oleic (O) and punicic (P) acids. The method is based on the absorbance ratio of released punicic acid from the hydrolysis of sn-POP (sn-1,3 regiospecific lipases) and sn-OPO (sn-2 regiospecific lipases).
View Article and Find Full Text PDFNon-Categorical Analyses Identify Rotenone-Induced 'Parkinsonian' Rats Benefiting from Nano-Emulsified Punicic Acid (Nano-PSO) in a Phenotypically Diverse Population: Implications for Translational Neurodegenerative Therapies.
Int J Mol Sci
November 2024
Laboratorio de Biología de Sistemas, Departamento de Biología Celular y Fisiología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
The pursuit of nutraceuticals to improve the quality of life for patients with neurodegenerative conditions is a dynamic field within neuropharmacology. Unfortunately, many nutraceuticals that show promise in preclinical studies fail to demonstrate significant clinical benefits in human trials, leading to their exclusion as therapeutic options. This discrepancy may stem from the categorical interpretation of preclinical and clinical results.
View Article and Find Full Text PDFAntiangiogenic Potential of Pomegranate Extracts.
Plants (Basel)
November 2024
Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali (DiSTeBA), Università del Salento, Via Prov.le Lecce Monteroni, 73100 Lecce, Italy.
Pomegranate ( L.) has long been recognised for its rich antioxidant profile and potential health benefits. Recent research has expanded its therapeutic potential to include antiangiogenic properties, which are crucial for inhibiting the growth of tumours and other pathological conditions involving aberrant blood vessel formation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!