Background: In times of the corona virus disease 2019 (COVID-19) pandemic, due to the urgent need to respond quickly to the challenges posed by the introduction of a new etiological agent and the peculiarity of the disease, which poses risks to people's lives and health, the use of digital technologies for monitoring and surveillance have been used as a means of fighting coronavirus. Thus, this study will identify the use of digital technologies to monitor, identify contacts and track transmission chains of COVID-19 worldwide.
Methods: The systematic review of this protocol will follow the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes Protocols. We will include studies that present digital technologies used in the monitoring of infected people, contact identification and the transmission chain of COVID-19 developed worldwide. For the selection of articles, the following databases will be consulted: PubMed, EMBASE, LILACS, Web of Science, Science Direct, Scopus, Livivo and CINAHL. In addition, we will conduct extensive research on selected sources of gray literature, including bibliographic databases, web-based search engines, practice-oriented magazines and government websites. Data extraction will take place in 2 stages (1- title and abstract screening and 2- full-text screening) and will be carried out independently by 2 reviewers, using the Mendeley software and the Rayyan QCRI application. The studies will be characterized as to the type and design of the study in relation to the ease in demonstrating the technologies used and the type of information produced. If it is necessary to synthesize quantitative data, the heterogeneity assessment will be performed using I2 statistics, and the meta-analysis will be processed using Review Manager 5.3.
Results: The development of this research will allow the knowledge of how these technologies were applied according to each territory and their effectiveness in reducing cases of COVID-19.
Conclusion: The results of this review can reveal the importance of modern technologies for reducing cases of COVID-19 and that these measures can be adopted by governments, organizations and for everyone.
Record Of Systematic Review: CRD42020211744.
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http://dx.doi.org/10.1097/MD.0000000000023744 | DOI Listing |
Sci Rep
January 2025
School of Electrical Engineering, Nanjing Vocational University of Industry Technology, Nanjing, 210023, China.
Transitioning to a power system heavily reliant on renewable wind energy involves more than just replacing conventional fossil-fuel-based power plant with wind farms, the wind energy must be able to meet the requirement of voltage establishment and power balance. It is believed that the self synchronized voltage source control of DFIG wind turbine generator is one of the possible solutions to realize virtual inertia and is helpful to increase the frequency stability of power system, thus is meaningful in the transformation of the power system dominated by renewable energy. Plenty of research has been conducted on the self synchronized voltage source control strategy in steady state, but few research is focused on the soft grid integration, which is a complicated process involving wind turbine control and power converter control.
View Article and Find Full Text PDFDiscov Oncol
January 2025
Department of Respiratory Medicine, The First Hospital of Jiaxing (Affiliated Hospital of Jiaxing University), 1882 South Zhonghuan Road, Jiaxing, 314000, Zhejiang, China.
Objective: The purpose of this study is to analyze the predictive value of neutrophil to lymphocyte ratio (NLR), lymphocyte count to monocyte count ratio (LMR), platelet to lymphocyte ratio (PLR), platelet count multiplied by neutrophil count to lymphocyte count ratio (SII), red blood cell distribution width (RDW), packed cell volume (PCV), and plateletcrit (PCT) levels in advanced non-small cell lung cancer (NSCLC) patients treated with PD-1/PD-L1 inhibitors.
Materials And Methods: From March 2019 to August 2023, we screened 104 of 153 patients with stage III unresectable local advanced NSCLC and IV NSCLC who received PD-1/PD-L1 inhibitor therapy at our hospital and met the inclusion and exclusion criteria for analysis. All patients were collected for clinical information, including baseline blood indicator (NLR, PLR, LMR, SII, CRP, RDW, PCV and PCT) levels before PD-1/PD-L1 inhibitor therapy and blood indicator levels and imaging evaluation results every two cycles after PD-1/PD-L1 inhibitor therapy.
NPJ Digit Med
January 2025
Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Large-scale and detailed analyses of activity in the United States (US) remain limited. In this work, we leveraged the comprehensive wearable, demographic, and survey data from the All of Us Research Program, the largest and most diverse population health study in the US to date, to apply and extend the previous global findings on activity inequality within the context of the US. We found that daily steps differed by sex at birth, age, body characteristics, geography, and built environment.
View Article and Find Full Text PDFBMC Health Serv Res
January 2025
Logistics Education (LEED) at Kühne Foundation, Hamburg, Germany.
Background: To ensure the complete traceability of healthcare commodities, robust end-to-end data management protocols are needed for the supply chain. In Ethiopia, digital tools like Dagu-2 are used in the lower levels of the healthcare supply chain. However, there is a lack of information regarding the implementation status, factors, and challenges of Dagu-2, as it is a recent upgrade from the offline Dagu-1 application.
View Article and Find Full Text PDFTrends Pharmacol Sci
January 2025
School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China; Western (Chongqing) Collaborative Innovation Center for Intelligent Diagnostics and Digital Medicine, Chongqing National Biomedicine Industry Park, Chongqing 401329, China. Electronic address:
Synthetic binding proteins (SBPs) are a class of protein binders that are artificially created and do not exist naturally. Their broad applications in tackling challenges of research, diagnostics, and therapeutics have garnered significant interest. Traditional protein engineering is pivotal to the discovery of SBPs.
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