Ki67 Assessment in Breast Cancer: Are We There Yet?

J Natl Cancer Inst

Fred Hutchinson Cancer Research Center, University of Washington and Seattle Cancer Care Alliance, Seattle, WA, USA.

Published: July 2021

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246841PMC
http://dx.doi.org/10.1093/jnci/djaa202DOI Listing

Publication Analysis

Top Keywords

ki67 assessment
4
assessment breast
4
breast cancer
4
cancer yet?
4
ki67
1
breast
1
cancer
1
yet?
1

Similar Publications

Dermatofibrosarcoma protuberans: A clinical and pathological observational report of Asian samples from one center.

J Cancer Res Ther

December 2024

Department of Plastic and Reconstructive Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Background: Dermatofibrosarcoma protuberans (DFSP) is a rare, low-grade fibrohistiocytic tumor with malignant potential. It is considered to have a high local recurrence rate due to the characteristic invasion of the finger-like lesion into the soft tissues.

Method: This retrospective study presents details of 20 DFSP patients with a history of surgery and a long follow-up period.

View Article and Find Full Text PDF

Ovarian cancer (OC) is a significant cause of cancer-related mortality among women. This study explores the efficacy of L. () extract, known for its phytoestrogenic properties, in treating OC through hormonal and metabolic modulation.

View Article and Find Full Text PDF

Interpretable CT Radiomics-based Machine Learning Model for Preoperative Prediction of Ki-67 Expression in Clear Cell Renal Cell Carcinoma.

Acad Radiol

January 2025

Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China (Y.X., B.X., Z.W., C.P., M.X.). Electronic address:

Rationale And Objectives: To develop and externally validate interpretable CT radiomics-based machine learning (ML) models for preoperative Ki-67 expression prediction in clear cell renal cell carcinoma (ccRCC).

Methods: 506 patients were retrospectively enrolled from three independent institutes and divided into the training (n=357) and external test (n=149) sets. Ki67 expression was determined by immunohistochemistry (IHC) and categorized into low (<15%) and high (≥15%) expression groups.

View Article and Find Full Text PDF

Background: Adrenocortical cancer (ACC) is rare and aggressive, with YAP1 overexpression associated with poor outcomes in pediatric patients. In this study, we investigated the mechanisms by which YAP1 drives ACC progression and explored it as a potential target therapy.

Methods: YAP1 expression and methylation in ACC were analyzed from pediatric and adult cohorts.

View Article and Find Full Text PDF

E-cigarettes (E.cigs) cause inflammation and damage to human organs, including the lungs and heart. In the gut, E.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!