AI Article Synopsis

  • The aldosterone-to-renin ratio (ARR) is frequently used to screen for primary aldosteronism in people with high blood pressure, but its accuracy can be compromised by various factors.
  • The review identifies key influences on the ARR, including sex, age, posture, and sodium intake, while noting that assay techniques do not impact the results.
  • Additionally, the effects of race and body mass index on the ARR remain unclear, emphasizing the importance of considering these factors to avoid misinterpretation of the test results.

Article Abstract

The aldosterone-to-renin ratio (ARR) is a common screening test for primary aldosteronism in hypertensives. However, there are many factors which could confound the ARR test result and reduce the accuracy of this test. The present review's objective is to identify these factors and to describe to what extent they affect the ARR. Our analysis revealed that sex, age, posture, and sodium-intake influence the ARR, whereas assay techniques do not. Race and body mass index have an uncertain effect on the ARR. We conclude that several factors can affect the ARR. Not taking these factors into account could lead to misinterpretation of the ARR.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8030008PMC
http://dx.doi.org/10.1111/jch.14117DOI Listing

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