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Right Atrial Thrombosis and Pulmonary Embolism: A Narrative Review. | LitMetric

AI Article Synopsis

  • Diagnosing pulmonary embolism (PE) is tough, often leading to delays in treatment, especially due to overlooked causes like mobile thrombus in the right cardiac chambers, which can be deadly.
  • The article highlights the particular danger of thrombus in the right atrial appendage (RAA), particularly in patients with atrial fibrillation, and reviews how different imaging techniques, like echocardiography and cardiac MRI, can help detect it.
  • There is a call for targeted searches for RAA thrombus in high-risk PE patients and development of tailored treatment protocols to improve outcomes for those affected by right cardiac thrombosis.

Article Abstract

Prompt diagnosis of pulmonary embolism (PE) remains challenging, which often results in a delayed or inappropriate treatment of this life-threatening condition. Mobile thrombus in the right cardiac chambers is a neglected cause of PE. It poses an immediate risk to life and is associated with an unfavorable outcome and high mortality. Thrombus residing in the right atrial appendage (RAA) is an underestimated cause of PE, especially in patients with atrial fibrillation. This article reviews achievements and challenges of detection and management of the right atrial thrombus with emphasis on RAA thrombus. The capabilities of transthoracic and transesophageal echocardiography and advantages of three-dimensional and two-dimensional echocardiography are reviewed. Strengths of cardiac magnetic resonance imaging (CMR), computed tomography, and cardiac ventriculography are summarized. We suggest that a targeted search for RAA thrombus is necessary in high-risk patients with PE and atrial fibrillation using transesophageal echocardiography and/or CMR when available independently on the duration of the disease. High-risk patients may also benefit from transthoracic echocardiography with right parasternal approach. The examination of high-risk patients should involve compression ultrasonography of lower extremity veins along with the above-mentioned technologies. Algorithms for RAA thrombus risk assessment and protocols aimed at identification of patients with RAA thrombosis, who will potentially benefit from treatment, are warranted. The development of treatment protocols specific for the diverse populations of patients with right cardiac thrombosis is important.

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Source
http://dx.doi.org/10.1055/s-0040-1718399DOI Listing

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