Targeted nanoscale therapeutics for myocardial infarction.

Biomater Sci

Department of Bioengineering and Sanford Consortium for Regenerative, Medicine, University of California, San Diego, La Jolla, USA.

Published: February 2021

Nanoscale therapeutics have promise for the administration of therapeutic small molecules and biologics to the heart following myocardial infarction. Directed delivery to the infarcted region of the heart using minimally invasive routes is critical to this promise. In this review, we will discuss the advances and design considerations for two nanoscale therapeutics engineered to target the infarcted heart, nanoparticles and adeno-associated viruses.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7932032PMC
http://dx.doi.org/10.1039/d0bm01677bDOI Listing

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