AI Article Synopsis
- * Regions where malaria is common have lower reported fatality rates from COVID-19 compared to malaria-free areas, suggesting a potential link between the two.
- * The study explores factors like CD-147, malaria-induced immunity, and the possibility of underreporting, indicating that understanding this relationship could aid in COVID-19 treatment and prevention.
Article Abstract
COVID-19 (coronavirus disease 2019) is a disease caused by the coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). COVID-19 has yielded many reported complications and unusual observations. In this article, we have reviewed one such observation: an association between malaria endemicity and reduced reported COVID-19 fatality. Malaria-endemic regions have a significantly lower reported COVID-19 fatality rate as compared to regions where malaria is non-endemic. Statistical analyses show that there is a strong negative correlation between the reported SARS-CoV-2 fatality and endemicity of malaria. In this review, we have discussed the potential role of CD-147, and potential malaria-induced immunity and polymorphisms in COVID-19 patients. Noteworthy, the results may also be due to underreported cases or due to the economic, political, and environmental differences between the malaria endemic and non-endemic countries. The study of this potential relationship might be of great help in COVID-19 therapy and prevention.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749783 | PMC |
| http://dx.doi.org/10.15190/d.2020.17 | DOI Listing |
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