AI Article Synopsis
- Hemolytic disease of the fetus and newborn is caused by maternal antibodies targeting the fetus, often linked to blood group incompatibilities.
- The use of anti-D gammaglobulin has reduced cases of Rh (D) sensitization, but minor blood group incompatibilities are increasingly significant in hemolytic disease cases.
- Clinical symptoms can range from mild hemolysis to severe conditions like hyperbilirubinemia, as illustrated in a case study involving hemolytic anemia due to anti-c antibody incompatibility.
Article Abstract
Hemolytic disease of the fetus and newborn is a disease that is caused by maternal alloantibodies to the fetus. In the literature, the frequency of hemolytic disease of the newborn due to Rh (D) sensitization decreased inversely with the increase in the use of anti-D gammaglobulin. However, the importance of minor blood group incompatibilities has increased in the etiology. Clinical presentation in patients with minor blood group incompatibility may vary from subclinical hemolysis findings to active hemolysis and hyperbilirubinemia requiring blood exchange. In this case study, we present a patient with hemolytic anemia due to anti-c antibody incompatibility.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751246 | PMC |
| http://dx.doi.org/10.14744/SEMB.2019.10693 | DOI Listing |
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