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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7751289 | PMC |
| http://dx.doi.org/10.2147/JPR.S295715 | DOI Listing |
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Racial and Ethnic Disparities in Fentanyl and Polysubstance Overdose Deaths.
JAMA Psychiatry
January 2025
Medical Scientist Training Program, School of Medicine, Virginia Commonwealth University, Richmond.
A quantitative LC-MS/MS method for investigation of polysubstance use involving heroin and cocaine.
J Pharm Biomed Anal
November 2024
Molecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, USA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, KY 40536, USA. Electronic address:
Article Synopsis
- * Researchers developed a highly accurate testing method to measure these drugs and their breakdown products in blood, adhering to regulatory guidelines.
- * Results show that using heroin and cocaine together significantly raises the risk of overdose, as heroin slows down cocaine clearance while cocaine boosts heroin metabolism, highlighting the complexities of polydrug use.
Understanding and Addressing Widening Racial Inequalities in Drug Overdose.
Am J Psychiatry
May 2024
UCLA Center for Social Medicine and Humanities (Friedman, Hansen); Department of Internal Medicine, Brigham and Women's Hospital, Boston (Nguemeni Tiako); UCLA Department of Psychiatry and Biobehavioral Sciences (Hansen).
The fourth wave of the United States overdose crisis-driven by the polysubstance use of fentanyl with stimulants and other synthetic substances-has driven sharply escalating racial/ethnic inequalities in drug overdose death rates. Here the authors present a detailed portrait of the latest overdose trends and synthesize the literature to describe where, how, and why these inequalities are worsening. By 2022 overdose deaths among Native and Black Americans rose to 1.
View Article and Find Full Text PDFEducational Attainment and US Drug Overdose Deaths.
JAMA Health Forum
October 2023
RAND, Arlington, Virginia.
Importance: Educational attainment in the US is associated with life expectancy. As the opioid crisis worsens, it is critical to understand how overdose death rate trends evolve across education groups.
Objective: To investigate the association between educational attainment and overdose death rates, with emphasis on trends during the COVID-19 pandemic.
The motives and methods of methamphetamine and 'heroin' co-use in West Virginia.
Harm Reduct J
July 2023
Department of Family and Community Medicine, University of California, 500 Parnassus Avenue, MU3E, San Francisco, CA, 94143, USA.
Background: Opioid and methamphetamine co-use is increasing across the USA with overdoses involving these drugs also rising. West Virginia (WV) has led the US in opioid overdose death rates since at least 2013 and rising co-use of methamphetamine with opioids has played a greater role in deaths over the last 5 years.
Methods: This study used rapid ethnography to examine methods and motivations behind opioids and methamphetamine co-use from the viewpoint of their consumers.
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