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| http://dx.doi.org/10.1007/s13193-020-01175-7 | DOI Listing |
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Traumatic brain injury (TBI) is a leading cause of mortality and disability worldwide and can lead to secondary sequelae such as increased seizure susceptibility. Emerging work suggests that the thalamus, the relay center of the brain that undergoes secondary damage after cortical TBI, is involved with heightened seizure risks after TBI. TBI also induces the recruitment of peripheral immune cells, including T cells, to the site(s) of injury, but it is unclear how these cells impact neurological sequelae post-TBI.
View Article and Find Full Text PDFMicrofilaria in the Urine of a Dog with Concurrent Urinary Bladder Sarcoma.
J Am Anim Hosp Assoc
January 2025
From the Department of Veterinary Clinical Services, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota (N.S., A.H., D.H.).
A 12 yr old female spayed American Staffordshire terrier was referred for stranguria, pollakiuria, and concern for a mass in the trigone of the urinary bladder. A urinalysis and abdominal ultrasound were performed to further investigate the bladder mass. Nematode larvae were identified in the urine, termed microfilaruria, while a caudal abdominal mass was found on ultrasound impinging on the urethra.
View Article and Find Full Text PDFCardiovascular Safety of Anti-CGRP Monoclonal Antibodies in Older Adults or Adults With Disability With Migraine.
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January 2025
Geriatric Research Education and Clinical Center, North Florida/South Georgia Veterans Health System, Gainesville, Florida.
Importance: Monoclonal antibodies (mAbs) targeting calcitonin gene-related peptide (CGRP) or its receptor (anti-CGRP mAbs) offer effective migraine-specific preventive treatment. However, concerns exist about their potential cardiovascular risks due to CGRP blockade.
Objective: To compare the incidence of cardiovascular disease (CVD) between Medicare beneficiaries with migraine who initiated anti-CGRP-mAbs vs onabotulinumtoxinA in the US.
Development and feasibility testing of a new device for home-based leg heat therapy in patients with lower extremity peripheral artery disease.
J Vasc Surg Cases Innov Tech
February 2025
Department of Health and Kinesiology, Purdue University, West Lafayette, IN.
People with symptomatic lower extremity peripheral artery disease (PAD) suffer from severe leg pain, walking impairment, and reduced quality of life, but few effective treatments are available. Emerging evidence suggests that regular heat therapy (HT) may improve cardiovascular and physical function in patients with PAD. However, the lack of accessible, practical modalities for unsupervised HT, especially for elderly individuals, has hindered clinical implementation.
View Article and Find Full Text PDFAcute Arterial Ischemia Secondary to Intrapelvic Acetabular Migration: A Multidisciplinary Approach.
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Vascular Surgery, Centro Médico Nacional 20 de Noviembre, Mexico City, MEX.
This case report evaluates current diagnostic and treatment approaches for intrapelvic acetabular migration, focusing on the rare but serious complication of acute limb ischemia following hip arthroplasty. A 67-year-old female with a history of total hip arthroplasty 10 years ago presented with acute limb ischemia after experiencing a traumatic event 72 hours prior, which had caused displacement of her hip prosthesis. Notably, she had a history of a traumatic event two years earlier for which she had been advised to undergo surgical correction, which she had refused.
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