Pasireotide improves hypercortisolemia and induces hyperglycemia via somatostatin receptor type-5 stimulation. GLP-1RA and SGLT2 inhibitor potentially help regulate hyperglycemia in patients with Cushing's disease, especially after pasireotide administration.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7752440PMC
http://dx.doi.org/10.1002/ccr3.3230DOI Listing

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