This report, prepared by a lead researcher, describes 2 independent, but similarly designed, clinical trials that were conducted to investigate the effectiveness, mechanisms, and predictors of electroacupuncture (EA) for treating chronic low-back pain (CLBP). Both trials recruited adults (ages 21-65) who had CLBP with an intensity ≥4/10 and a duration ≥6 months. Verum EA or sham EA was administered twice per week for 6-8 weeks. The common outcome between the 2 studies was the patients' responses to the Roland Morris Disability Questionnaire. Using least absolute shrinkage and selection operator (LASSO), the authors were able to predict clinical outcome in the second study by using a prediction model based on data from the first study. This work demonstrated the feasibility of predicting clinical outcomes when using acupuncture for treating CLBP.
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http://dx.doi.org/10.1089/acu.2020.1495 | DOI Listing |
J Neurophysiol
January 2025
School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province, China.
Parkinson's disease (PD) is a prevalent and challenging neurodegenerative disorder, and may involve impaired autophagy. Nuclear factor erythroid-2-related factor 2 (Nrf2) is crucial for regulating autophagy-related genes, maintaining cellular homeostasis. Electroacupuncture (EA), a complementary and alternative therapy for PD, has gained widespread clinical application.
View Article and Find Full Text PDFMed Acupunct
October 2024
School of acupuncture-moxibustion and tuina, Anhui University of Chinese Medicine, Hefei City, China.
Background: Chronic nonspecific low back pain (cNLBP) can be effectively treated by electroacupuncture (EA) at traditional acupoints (TAPs) and myofascial trigger points (MTrPs). However, the optimal type and frequency of stimulation (alternated frequency [AF] and high frequency [HF]) remain unclear. This study aimed to explore this.
View Article and Find Full Text PDFMed Acupunct
October 2024
Department of Family Medicine, West Virginia University, Morgantown, West Virginia, USA.
Objective: Stiff person syndrome (SPS) is a rare neurological disorder. Treatments are limited, and non-pharmacologic therapies are recommended based on symptomatology. A G2P2002 post-menopausal 60-year-old female with hypertension, obesity, and type II diabetes, and SPS secondary to a paraneoplastic process cause by endometrioid ovarian adenocarcinoma who presented to acupuncture clinic seeking treatment for SPS and its sequela.
View Article and Find Full Text PDFBMC Complement Med Ther
December 2024
Division of internal Medicine, Institute of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Introduction: Sarcopenia is a disease primarily characterized by age-related loss of skeletal muscle mass, muscle strength, and/or decline in physical performance. Sarcopenia has an insidious onset which can cause functional impairment in the body and increase the risk of falls and disability in the elderly. It significantly increases the likelihood of fractures and mortality, severely impairing the quality of life and health of the elderly people.
View Article and Find Full Text PDFNan Fang Yi Ke Da Xue Xue Bao
December 2024
Innovation and Transformation Center, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China.
Objectives: To explore the neuroprotective mechanism of electroacupuncture at the acupoints and in rats with cerebral ischemia-reperfusion (IR) injury.
Methods: Forty-eight male SD rats were equally randomized into sham operation group, cerebral IR model group, acupoint electroacupuncture group and non-acupoint acupuncture group. In the latter 3 groups, cerebral focal ischemic injury was induced using the Longa method; in the two electroacupuncture groups, electroacupuncture was performed either at the acupoints and or at non-acupoint sites for 7 days.
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