AI Article Synopsis
- Plasticity helps brain cells change and adapt when they get activated in different ways.
- People usually think about how nerve cells (neurons) change, but it turns out that other cells called astrocytes play a big role too.
- This article talks about the latest discoveries about astrocytes and explains why they are really important for how the brain can adapt and change.
Article Abstract
Plasticity is a fundamental property of neuronal circuits, allowing them to adapt to alterations in activation. Generally speaking, plasticity has been viewed from a 'neuron-centric' perspective, with changes in circuit function attributed to alterations in neuronal excitability, synaptic strength or neuronal connectivity. However, it is now clear that glial cells, in particular astrocytes, are key regulators of neuronal plasticity. This article reviews recent progress made in understanding astrocyte function and attempts to summarize these functions into a coherent framework that positions astrocytes as central players in the plasticity process.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202513 | PMC |
| http://dx.doi.org/10.1016/j.conb.2020.12.001 | DOI Listing |
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